Literature DB >> 28342946

NegAIT: A new parser for medical text simplification using morphological, sentential and double negation.

Partha Mukherjee1, Gondy Leroy2, David Kauchak3, Srinidhi Rajanarayanan2, Damian Y Romero Diaz2, Nicole P Yuan2, T Gail Pritchard2, Sonia Colina2.   

Abstract

Many different text features influence text readability and content comprehension. Negation is commonly suggested as one such feature, but few general-purpose tools exist to discover negation and studies of the impact of negation on text readability are rare. In this paper, we introduce a new negation parser (NegAIT) for detecting morphological, sentential, and double negation. We evaluated the parser using a human annotated gold standard containing 500 Wikipedia sentences and achieved 95%, 89% and 67% precision with 100%, 80%, and 67% recall, respectively. We also investigate two applications of this new negation parser. First, we performed a corpus statistics study to demonstrate different negation usage in easy and difficult text. Negation usage was compared in six corpora: patient blogs (4K sentences), Cochrane reviews (91K sentences), PubMed abstracts (20K sentences), clinical trial texts (48K sentences), and English and Simple English Wikipedia articles for different medical topics (60K and 6K sentences). The most difficult text contained the least negation. However, when comparing negation types, difficult texts (i.e., Cochrane, PubMed, English Wikipedia and clinical trials) contained significantly (p<0.01) more morphological negations. Second, we conducted a predictive analytics study to show the importance of negation in distinguishing between easy and difficulty text. Five binary classifiers (Naïve Bayes, SVM, decision tree, logistic regression and linear regression) were trained using only negation information. All classifiers achieved better performance than the majority baseline. The Naïve Bayes' classifier achieved the highest accuracy at 77% (9% higher than the majority baseline).
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Health literacy; NLP; Negation; Readability; Text simplification

Mesh:

Year:  2017        PMID: 28342946      PMCID: PMC5933936          DOI: 10.1016/j.jbi.2017.03.014

Source DB:  PubMed          Journal:  J Biomed Inform        ISSN: 1532-0464            Impact factor:   6.317


  27 in total

1.  Negation and its impact on the accessibility of text information.

Authors:  B Kaup
Journal:  Mem Cognit       Date:  2001-10

2.  Effects of negation and situational presence on the accessibility of text information.

Authors:  Barbara Kaup; Rolf A Zwaan
Journal:  J Exp Psychol Learn Mem Cogn       Date:  2003-05       Impact factor: 3.051

3.  Changes in activation levels with negation.

Authors:  M C MacDonald; M A Just
Journal:  J Exp Psychol Learn Mem Cogn       Date:  1989-07       Impact factor: 3.051

4.  The effect of physician-patient collaboration on patient adherence in non-psychiatric medicine.

Authors:  Alexis Arbuthnott; Donald Sharpe
Journal:  Patient Educ Couns       Date:  2009-04-22

5.  The effect of word familiarity on actual and perceived text difficulty.

Authors:  Gondy Leroy; David Kauchak
Journal:  J Am Med Inform Assoc       Date:  2013-10-07       Impact factor: 4.497

6.  DEEPEN: A negation detection system for clinical text incorporating dependency relation into NegEx.

Authors:  Saeed Mehrabi; Anand Krishnan; Sunghwan Sohn; Alexandra M Roch; Heidi Schmidt; Joe Kesterson; Chris Beesley; Paul Dexter; C Max Schmidt; Hongfang Liu; Mathew Palakal
Journal:  J Biomed Inform       Date:  2015-03-16       Impact factor: 6.317

7.  How (not) to inform patients about drug use: use and effects of negations in Dutch patient information leaflets.

Authors:  Christian Burgers; Camiel J Beukeboom; Lisa Sparks; Vera Diepeveen
Journal:  Pharmacoepidemiol Drug Saf       Date:  2014-07-15       Impact factor: 2.890

8.  How the doc should (not) talk: when breaking bad news with negations influences patients' immediate responses and medical adherence intentions.

Authors:  Christian Burgers; Camiel J Beukeboom; Lisa Sparks
Journal:  Patient Educ Couns       Date:  2012-08-29

9.  Measuring Text Difficulty Using Parse-Tree Frequency.

Authors:  David Kauchak; Gondy Leroy; Alan Hogue
Journal:  J Assoc Inf Sci Technol       Date:  2017-06-20       Impact factor: 2.687

10.  Closing the loop: physician communication with diabetic patients who have low health literacy.

Authors:  Dean Schillinger; John Piette; Kevin Grumbach; Frances Wang; Clifford Wilson; Carolyn Daher; Krishelle Leong-Grotz; Cesar Castro; Andrew B Bindman
Journal:  Arch Intern Med       Date:  2003-01-13
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  7 in total

1.  Using Lexical Chains to Identify Text Difficulty: A Corpus Statistics and Classification Study.

Authors:  Partha Mukherjee; Gondy Leroy; David Kauchak
Journal:  IEEE J Biomed Health Inform       Date:  2018-12-06       Impact factor: 5.772

2.  The Role of Surface, Semantic and Grammatical Features on Simplification of Spanish Medical Texts: A User Study.

Authors:  Partha Mukherjee; Gondy Leroy; David Kauchak; Brianda Armenta Navarrete; Damian Y Diaz; Sonia Colina
Journal:  AMIA Annu Symp Proc       Date:  2018-04-16

3.  High Throughput Phenotyping for Dimensional Psychopathology in Electronic Health Records.

Authors:  Thomas H McCoy; Sheng Yu; Kamber L Hart; Victor M Castro; Hannah E Brown; James N Rosenquist; Alysa E Doyle; Pieter J Vuijk; Tianxi Cai; Roy H Perlis
Journal:  Biol Psychiatry       Date:  2018-02-26       Impact factor: 13.382

4.  Improving the Quality of Suggestions for Medical Text Simplification Tools.

Authors:  David Kauchak; Jorge Apricio; Gondy Leroy
Journal:  AMIA Annu Symp Proc       Date:  2022-05-23

5.  Paragraph-level Simplification of Medical Texts.

Authors:  Ashwin Devaraj; Byron C Wallace; Iain J Marshall; Junyi Jessy Li
Journal:  Proc Conf       Date:  2021-06

Review 6.  Natural Language Processing for EHR-Based Computational Phenotyping.

Authors:  Zexian Zeng; Yu Deng; Xiaoyu Li; Tristan Naumann; Yuan Luo
Journal:  IEEE/ACM Trans Comput Biol Bioinform       Date:  2018-06-25       Impact factor: 3.710

7.  Cross Disciplinary Consultancy to Bridge Public Health Technical Needs and Analytic Developers: Negation Detection Use Case.

Authors:  Mike Conway; Danielle Mowery; Amy Ising; Sumithra Velupillai; Son Doan; Julia Gunn; Michael Donovan; Caleb Wiedeman; Lance Ballester; Karl Soetebier; Catherine Tong; Howard Burkom
Journal:  Online J Public Health Inform       Date:  2018-09-21
  7 in total

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