| Literature DB >> 28342822 |
Cesar Sepúlveda1, Iván Palomo2, Eduardo Fuentes3.
Abstract
Beyond its function in hemostasis, platelets activation has an important role in cardiovascular diseases (CVD) development. There are different clinical conditions that can mediate abnormal platelet activation and favors pathological thrombosis and CVD. These include Hypertension, diabetes and dyslipidemia, all risks factors from CVD development. Different drugs employed in the handled of these conditions have showed decreases platelet activation and related markers. This effect is in part by improved the base condition; however someone of these drugs can modulate platelet targets. We discuss about underlying mechanisms and the possible implications in the treatment of CVD.Entities:
Keywords: Antiplatelet; Cardiovascular diseases; Diabetes; Drugs; Hypertension
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Year: 2017 PMID: 28342822 DOI: 10.1016/j.vph.2017.03.004
Source DB: PubMed Journal: Vascul Pharmacol ISSN: 1537-1891 Impact factor: 5.773