Literature DB >> 28342189

Straight-to-test colonoscopy for 2-week-wait referrals improves time to diagnosis of colorectal cancer and is feasible in a high-volume unit.

A Banerjea1, J Voll1, A Chowdhury1, A Siddika1, S Thomson1, R Briggs1, D J Humes1,2.   

Abstract

AIM: We have introduced 'straight-to-test' (STT) colonoscopy as part of our 2-week-wait (2WW) pathway to address increasing numbers of urgent referrals for colorectal cancer (CRC) within the National Health Service. In this study we evaluated the ability of this initiative to shorten the time to diagnosis of CRC.
METHOD: We amended our 2WW referral form to include performance status and comorbidities. General practitioners were asked to provide data on estimated glomerular filtration rate and full blood count/ferritin. Our 2WW referrals were screened by a colorectal consultant and a nurse specialist. Those deemed unsuitable for STT were offered outpatient assessment (OPA).
RESULTS: Of 553 2WW referrals screened, 352 were considered suitable, 65 of whom failed a telephone assessment or were uncontactable, and accordingly 287 were offered the STT pathway. The STT group was significantly younger than the OPA group (median 65.9 years vs 78.7 years; P < 0.0001). STT colonoscopy significantly reduced the time to first test (13 days vs 22 days; P < 0.0001) and tissue diagnosis from the referral date (17 days vs 24.5 days; P < 0.0001). Thirty-seven (6.8%) CRCs were detected. Proportionately fewer patients in the STT pathway were managed with 'best supportive care only' compared with patients attending OPA (one of 15 vs six of 22, respectively). STT colonoscopy obviated the need for clinic attendance before testing in 287 patients, representing a potential net cost benefit of at least £48 500 in 4 months.
CONCLUSION: STT colonoscopy was safe and effective for selecting out a group of symptomatic patients who could proceed straight to endoscopic examination and receive a diagnosis more rapidly. Colorectal Disease
© 2017 The Association of Coloproctology of Great Britain and Ireland.

Entities:  

Keywords:  2-week-wait pathway; Colonoscopy; colorectal cancer; straight-to-test

Mesh:

Year:  2017        PMID: 28342189     DOI: 10.1111/codi.13667

Source DB:  PubMed          Journal:  Colorectal Dis        ISSN: 1462-8910            Impact factor:   3.788


  7 in total

1.  Straight-to-test for the two-week-wait colorectal cancer pathway under the updated NICE guidelines reduces time to cancer diagnosis and treatment.

Authors:  J Christopher; T R Flint; H Ahmed; N Dhir; R Li; K Macfarland; Dzs Ng; Jmk Ng; C O'Neill; A Te Water Naudé; K Sloan; N R Hall; M P Powar
Journal:  Ann R Coll Surg Engl       Date:  2019-05       Impact factor: 1.891

2.  Is qFIT a useful tool in prioritising symptomatic patients referred with suspect colorectal cancer in the COVID-19 era?

Authors:  Sarah Small; Rachael Coulson; Robert Spence; Ian McAllister
Journal:  Ulster Med J       Date:  2022-06-15

3.  Service evaluation of faecal immunochemical testing and anaemia for risk stratification in the 2-week-wait pathway for colorectal cancer.

Authors:  C Chapman; J Bunce; S Oliver; O Ng; A Tangri; R Rogers; R F Logan; D J Humes; A Banerjea
Journal:  BJS Open       Date:  2019-01-28

4.  Anaemia as a risk stratification tool for symptomatic patients referred via the two-week wait pathway for colorectal cancer.

Authors:  S Mashlab; P Large; W Laing; O Ng; M D'Auria; D Thurston; S Thomson; A G Acheson; D J Humes; A Banerjea
Journal:  Ann R Coll Surg Engl       Date:  2018-03-15       Impact factor: 1.891

5.  Attitudes towards faecal immunochemical testing in patients at increased risk of colorectal cancer: an online survey of GPs in England.

Authors:  Christian von Wagner; Sandro Stoffel; Madeleine Freeman; Helga Laszlo; Brian D Nicholson; Jessican Sheringham; Dorothy Szinay; Yasemin Hirst
Journal:  Br J Gen Pract       Date:  2018-10-08       Impact factor: 5.386

6.  Faecal immunochemical testing and blood tests for prioritization of urgent colorectal cancer referrals in symptomatic patients: a 2-year evaluation.

Authors:  J A Bailey; J Weller; C J Chapman; A Ford; K Hardy; S Oliver; J R Morling; J A Simpson; D J Humes; A Banerjea
Journal:  BJS Open       Date:  2021-03-05

7.  "One stop" clinic for upper gastrointestinal cancer-an alternative to "straight to test" referrals?

Authors:  Marina Yiasemidou; Ross Lathan; Manfred Lambertz; Chitakattil Oommen; Ian Chetter
Journal:  Ir J Med Sci       Date:  2021-07-20       Impact factor: 1.568

  7 in total

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