Literature DB >> 2834217

Effect of NCO-700, an inhibitor of thiol protease, on reactive oxygen production by chemotactic peptide-stimulated rabbit peripheral granulocytes.

K Tawara1, S Fujisawa, K Nakai.   

Abstract

The specific thiol protease inhibitor, NCO-700, which is related to L-trans-epoxysuccinylpeptides, inhibited oxidant production by chemoattractant-stimulated rabbit polymorphonuclear leukocytes. NCO-700 could also scavenge active oxygen generated from sodium hypochlorite-hydrogen peroxide and hypoxanthine-xanthine oxidase systems.

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Year:  1988        PMID: 2834217     DOI: 10.1007/BF01961277

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  11 in total

1.  Protease inhibitors antagonize the activation of polymorphonuclear leukocyte oxygen consumption.

Authors:  B D Goldstein; G Witz; M Amoruso; W Troll
Journal:  Biochem Biophys Res Commun       Date:  1979-06-13       Impact factor: 3.575

2.  Association of neutrophil chemiluminescence with microbicidal activity.

Authors:  T D Horan; D English; T A McPherson
Journal:  Clin Immunol Immunopathol       Date:  1982-02

3.  A potential role for hypochlorous acid in granulocyte-mediated tumor cell cytotoxicity.

Authors:  A Slivka; A F LoBuglio; S J Weiss
Journal:  Blood       Date:  1980-02       Impact factor: 22.113

4.  Co-oxidation of luminol by hypochlorite and hydrogen peroxide implications for neutrophil chemiluminescence.

Authors:  E P Brestel
Journal:  Biochem Biophys Res Commun       Date:  1985-01-16       Impact factor: 3.575

5.  Reduction of experimentally produced acute myocardial infarction size by a new synthetic inhibitor, NCO-700, against calcium-activated neutral protease.

Authors:  T Toyo-oka; T Kamishiro; M Masaki; T Masaki
Journal:  Jpn Heart J       Date:  1982-09

6.  Purification and characterization of cathepsin B from monkey skeletal muscle.

Authors:  T Hirao; K Hara; K Takahashi
Journal:  J Biochem       Date:  1984-03       Impact factor: 3.387

7.  Long-lived oxidants generated by human neutrophils: characterization and bioactivity.

Authors:  S J Weiss; M B Lampert; S T Test
Journal:  Science       Date:  1983-11-11       Impact factor: 47.728

8.  Evidence that proteases are involved in superoxide production by human polymorphonuclear leukocytes and monocytes.

Authors:  S Kitagawa; F Takaku; S Sakamoto
Journal:  J Clin Invest       Date:  1980-01       Impact factor: 14.808

9.  Monocyte and granulocyte-mediated tumor cell destruction. A role for the hydrogen peroxide-myeloperoxidase-chloride system.

Authors:  S J Weiss; A Slivka
Journal:  J Clin Invest       Date:  1982-02       Impact factor: 14.808

10.  Inhibition of neutrophil sulfhydryl groups by choloromethyl ketones. A mechanism for their inhibition of superoxide production.

Authors:  M F Tsan
Journal:  Biochem Biophys Res Commun       Date:  1983-04-29       Impact factor: 3.575

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  1 in total

1.  Oxidation of defined antigens allows protein unfolding and increases both proteolytic processing and exposes peptide epitopes which are recognized by specific T cells.

Authors:  E Carrasco-Marín; J E Paz-Miguel; P López-Mato; C Alvarez-Domínguez; F Leyva-Cobián
Journal:  Immunology       Date:  1998-11       Impact factor: 7.397

  1 in total

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