| Literature DB >> 28341256 |
Monika Sienkiewicz1, Monika Łysakowska2, Edward Kowalczyk3, Grażyna Szymańska4, Ewa Kochan4, Jolanta Krukowska5, Jurek Olszewski6, Hanna Zielińska-Bliźniewska7.
Abstract
The aim of this work was to characterize the ability of essential oils to support antibiotics against pathogenic bacteria in wounds. Gram-positive and Gram-negative bacteria obtained from wound infections were identified according to standard microbiological methods. Essential oils were analysed by GC-FID-MS. The susceptibility of bacteria to antibiotics, essential oils and their combination was assessed using the disc-diffusion method. The Minimal Inhibitory Concentration and Minimum Bactericidal Concentration of the essential oils were established by the micro-dilution broth method. Although cinnamon, clove, thyme and lavender essential oils were found to have the greatest antibacterial activity when used alone, the greatest additive and synergistic effects against pathogenic wound bacteria in combination with recommended antibiotics were demonstrated by basil, clary sage and rosemary oils. Copyright ÂEntities:
Keywords: Additive effect; Antibiotic resistance; Essential oils; Synergistic effect; Wound pathogens
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Year: 2016 PMID: 28341256 DOI: 10.1016/j.burns.2016.08.032
Source DB: PubMed Journal: Burns ISSN: 0305-4179 Impact factor: 2.744