Literature DB >> 28340683

TRPV4 Moves toward Center-Fold in Rosacea Pathogenesis.

Yong Chen1, Carlene D Moore1, Jennifer Y Zhang2, Russell P Hall2, Amanda S MacLeod2, Wolfgang Liedtke3.   

Abstract

Mascarenhas et al. report that TRPV4 expression is upregulated in mast cells in response to the proteolytic cathelicidin fragment LL37 in a murine rosacea model and that TRPV4 loss of function attenuates mast cell degranulation. These findings render TRPV4 a translational-medical target in rosacea. However, signaling mechanisms causing increased expression of TRPV4 await elucidation. Moreover, we ask whether TRPV4-mediated Ca++-influx evokes mast cell degranulation.
Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

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Year:  2017        PMID： 28340683      PMCID： PMC5536341          DOI： 10.1016/j.jid.2016.12.013

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  12 in total

1.  Warm temperatures activate TRPV4 in mouse 308 keratinocytes.

Authors:  Man-Kyo Chung; Hyosang Lee; Michael J Caterina
Journal:  J Biol Chem       Date:  2003-06-03       Impact factor: 5.157

2.  TRPV4 Mediates Mast Cell Activation in Cathelicidin-Induced Rosacea Inflammation.

Authors:  Nicholas L Mascarenhas; Zhenping Wang; Yu-Ling Chang; Anna Di Nardo
Journal:  J Invest Dermatol       Date:  2016-11-28       Impact factor: 8.551

3.  TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator.

Authors:  Nicole Alessandri-Haber; Elizabeth Joseph; Olayinka A Dina; Wolfgang Liedtke; Jon D Levine
Journal:  Pain       Date:  2005-10-05       Impact factor: 6.961

4.  Patients with rosacea have increased risk of dementia.

Authors:  Alexander Egeberg; Peter R Hansen; Gunnar H Gislason; Jacob P Thyssen
Journal:  Ann Neurol       Date:  2016-04-28       Impact factor: 10.422

5.  UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling.

Authors:  Carlene Moore; Ferda Cevikbas; H Amalia Pasolli; Yong Chen; Wei Kong; Cordula Kempkes; Puja Parekh; Suk Hee Lee; Nelly-Ange Kontchou; Iwei Yeh; Iwei Ye; Nan Marie Jokerst; Elaine Fuchs; Martin Steinhoff; Wolfgang B Liedtke
Journal:  Proc Natl Acad Sci U S A       Date:  2013-08-08       Impact factor: 11.205

6.  Cathelicidin peptide LL-37 increases UVB-triggered inflammasome activation: possible implications for rosacea.

Authors:  Suzanna Salzer; Sonja Kresse; Yoji Hirai; Sarah Koglin; Markus Reinholz; Thomas Ruzicka; Jürgen Schauber
Journal:  J Dermatol Sci       Date:  2014-09-28       Impact factor: 4.563

7.  Facilitation of TRPV4 by TRPV1 is required for itch transmission in some sensory neuron populations.

Authors:  Seungil Kim; Devin M Barry; Xian-Yu Liu; Shijin Yin; Admire Munanairi; Qing-Tao Meng; Wei Cheng; Ping Mo; Li Wan; Shen-Bin Liu; Kasun Ratnayake; Zhong-Qiu Zhao; Narasimhan Gautam; Jie Zheng; W K Ajith Karunarathne; Zhou-Feng Chen
Journal:  Sci Signal       Date:  2016-07-19       Impact factor: 9.517

8.  TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles.

Authors:  Jinju Li; Patrick Kanju; Michael Patterson; Wei-Leong Chew; Seung-Hyun Cho; Ian Gilmour; Tim Oliver; Ryohei Yasuda; Andrew Ghio; Sidney A Simon; Wolfgang Liedtke
Journal:  Environ Health Perspect       Date:  2011-01-18       Impact factor: 9.031

9.  Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch.

Authors:  Yong Chen; Quan Fang; Zilong Wang; Jennifer Y Zhang; Amanda S MacLeod; Russell P Hall; Wolfgang B Liedtke
Journal:  J Biol Chem       Date:  2016-03-09       Impact factor: 5.157

10.  Involvement of TRPV4 in Serotonin-Evoked Scratching.

Authors:  Tasuku Akiyama; Margaret Ivanov; Masaki Nagamine; Auva Davoodi; Mirela I Carstens; Akihiko Ikoma; Ferda Cevikbas; Cordula Kempkes; Joerg Buddenkotte; Martin Steinhoff; E Carstens
Journal:  J Invest Dermatol       Date:  2016-01       Impact factor: 8.551
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  8 in total

Review 1.  Cutaneous and ocular rosacea: Common and specific physiopathogenic mechanisms and study models.

Authors:  Daniela Rodrigues-Braz; Min Zhao; Nilufer Yesilirmak; Selim Aractingi; Francine Behar-Cohen; Jean-Louis Bourges
Journal:  Mol Vis       Date:  2021-05-13       Impact factor: 2.367

Review 2.  Cannabinoid Signaling in the Skin: Therapeutic Potential of the "C(ut)annabinoid" System.

Authors:  Kinga Fanni Tóth; Dorottya Ádám; Tamás Bíró; Attila Oláh
Journal:  Molecules       Date:  2019-03-06       Impact factor: 4.927

Review 3.  Multifaceted MRGPRX2: New insight into the role of mast cells in health and disease.

Authors:  Saptarshi Roy; Chalatip Chompunud Na Ayudhya; Monica Thapaliya; Vishwa Deepak; Hydar Ali
Journal:  J Allergy Clin Immunol       Date:  2021-05-04       Impact factor: 14.290

4.  Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes.

Authors:  Aida Olivan-Viguera; Angel Luis Garcia-Otin; Javier Lozano-Gerona; Edgar Abarca-Lachen; Ana J Garcia-Malinis; Kirk L Hamilton; Yolanda Gilaberte; Esther Pueyo; Ralf Köhler
Journal:  PLoS One       Date:  2018-01-02       Impact factor: 3.240

5.  Cinnamtannin B1 attenuates rosacea-like signs via inhibition of pro-inflammatory cytokine production and down-regulation of the MAPK pathway.

Authors:  Hung-Lin Kan; Chia-Chi Wang; Yin-Hua Cheng; Chi-Lung Yang; Hsun-Shuo Chang; Ih-Sheng Chen; Ying-Chi Lin
Journal:  PeerJ       Date:  2020-12-21       Impact factor: 2.984

Review 6.  Advances in TRP channel drug discovery: from target validation to clinical studies.

Authors:  Ari-Pekka Koivisto; Maria G Belvisi; Rachelle Gaudet; Arpad Szallasi
Journal:  Nat Rev Drug Discov       Date:  2021-09-15       Impact factor: 112.288

Review 7.  Rosacea: Epidemiology, pathogenesis, and treatment.

Authors:  Barbara M Rainer; Sewon Kang; Anna L Chien
Journal:  Dermatoendocrinol       Date:  2017-10-04

8.  Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis.

Authors:  Javier Lozano-Gerona; Aida Oliván-Viguera; Pablo Delgado-Wicke; Vikrant Singh; Brandon M Brown; Elena Tapia-Casellas; Esther Pueyo; Marta Sofía Valero; Ángel-Luis Garcia-Otín; Pilar Giraldo; Edgar Abarca-Lachen; Joaquín C Surra; Jesús Osada; Kirk L Hamilton; Siba P Raychaudhuri; Miguel Marigil; Ángeles Juarranz; Heike Wulff; Hiroto Miura; Yolanda Gilaberte; Ralf Köhler
Journal:  PLoS One       Date:  2020-03-09       Impact factor: 3.240
  8 in total

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