Literature DB >> 28339642

Meaningful use of health information technology and declines in in-hospital adverse drug events.

Michael F Furukawa1, William D Spector1, M Rhona Limcangco2, William E Encinosa1.   

Abstract

OBJECTIVE: Nationwide initiatives have promoted greater adoption of health information technology as a means to reduce adverse drug events (ADEs). Hospital adoption of electronic health records with Meaningful Use (MU) capabilities expected to improve medication safety has grown rapidly. However, evidence that MU capabilities are associated with declines in in-hospital ADEs is lacking.
METHODS: Data came from the 2010-2013 Medicare Patient Safety Monitoring System and the 2008-2013 Healthcare Information and Management Systems Society (HIMSS) Analytics Database. Two-level random intercept logistic regression was used to estimate the association of MU capabilities and occurrence of ADEs, adjusting for patient characteristics, hospital characteristics, and year of observation.
RESULTS: Rates of in-hospital ADEs declined by 19% from 2010 to 2013. Adoption of MU capabilities was associated with 11% lower odds of an ADE (95% confidence interval [CI], 0.84-0.96). Interoperability capability was associated with 19% lower odds of an ADE (95% CI, 0.67- 0.98). Adoption of MU capabilities explained 22% of the observed reduction in ADEs, or 67,000 fewer ADEs averted by MU. DISCUSSION: Concurrent with the rapid uptake of MU and interoperability, occurrence of in-hospital ADEs declined significantly from 2010 to 2013. MU capabilities and interoperability were associated with lower occurrence of ADEs, but the effects did not vary by experience with MU. About one-fifth of the decline in ADEs from 2010 to 2013 was attributable to MU capabilities.
CONCLUSION: Findings support the contention that adoption of MU capabilities and interoperability spurred by the Health Information Technology for Economic and Clinical Health Act contributed in part to the recent decline in ADEs. Published by Oxford University Press on behalf of the American Medical Informatics Association 2017. This work is written by US Government employees and is in the public domain in the United States.

Entities:  

Keywords:  adverse drug events; electronic health records; hospitals; interoperability; patient safety

Mesh:

Year:  2017        PMID: 28339642      PMCID: PMC7787251          DOI: 10.1093/jamia/ocw183

Source DB:  PubMed          Journal:  J Am Med Inform Assoc        ISSN: 1067-5027            Impact factor:   4.497


  16 in total

1.  Implementation of the federal health information technology initiative.

Authors:  David Blumenthal
Journal:  N Engl J Med       Date:  2011-12-22       Impact factor: 91.245

2.  Meaningful Use IT reduces hospital-caused adverse drug events even at challenged hospitals.

Authors:  William E Encinosa; Jaeyong Bae
Journal:  Healthc (Amst)       Date:  2014-08-08

3.  More than half of US hospitals have at least a basic EHR, but stage 2 criteria remain challenging for most.

Authors:  Julia Adler-Milstein; Catherine M DesRoches; Michael F Furukawa; Chantal Worzala; Dustin Charles; Peter Kralovec; Samantha Stalley; Ashish K Jha
Journal:  Health Aff (Millwood)       Date:  2014-08-07       Impact factor: 6.301

Review 4.  Health information technology: an updated systematic review with a focus on meaningful use.

Authors:  Spencer S Jones; Robert S Rudin; Tanja Perry; Paul G Shekelle
Journal:  Ann Intern Med       Date:  2014-01-07       Impact factor: 25.391

Review 5.  Racial and Ethnic Disparities in Adverse Drug Events: A Systematic Review of the Literature.

Authors:  Avi Baehr; Juliet C Peña; Dale J Hu
Journal:  J Racial Ethn Health Disparities       Date:  2015-03-24

6.  Patient safety at ten: unmistakable progress, troubling gaps.

Authors:  Robert M Wachter
Journal:  Health Aff (Millwood)       Date:  2009-12-01       Impact factor: 6.301

Review 7.  Implementing electronic health records in hospitals: a systematic literature review.

Authors:  Albert Boonstra; Arie Versluis; Janita F J Vos
Journal:  BMC Health Serv Res       Date:  2014-09-04       Impact factor: 2.655

8.  Explaining the decrease in U.S. deaths from coronary disease, 1980-2000.

Authors:  Earl S Ford; Umed A Ajani; Janet B Croft; Julia A Critchley; Darwin R Labarthe; Thomas E Kottke; Wayne H Giles; Simon Capewell
Journal:  N Engl J Med       Date:  2007-06-07       Impact factor: 91.245

Review 9.  Reduction in medication errors in hospitals due to adoption of computerized provider order entry systems.

Authors:  David C Radley; Melanie R Wasserman; Lauren Ew Olsho; Sarah J Shoemaker; Mark D Spranca; Bethany Bradshaw
Journal:  J Am Med Inform Assoc       Date:  2013-02-20       Impact factor: 4.497

Review 10.  The effectiveness of computerized order entry at reducing preventable adverse drug events and medication errors in hospital settings: a systematic review and meta-analysis.

Authors:  Teryl K Nuckols; Crystal Smith-Spangler; Sally C Morton; Steven M Asch; Vaspaan M Patel; Laura J Anderson; Emily L Deichsel; Paul G Shekelle
Journal:  Syst Rev       Date:  2014-06-04
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  5 in total

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Journal:  Appl Clin Inform       Date:  2018-01-03       Impact factor: 2.342

Review 2.  Impact of electronic health records on predefined safety outcomes in patients admitted to hospital: a scoping review.

Authors:  Christian Peter Subbe; Genevieve Tellier; Paul Barach
Journal:  BMJ Open       Date:  2021-01-13       Impact factor: 2.692

3.  Assessing Consistency of Drug-Drug Interaction-Related Information Across Various Drug Information Resources.

Authors:  Atiqulla Shariff; Sathvik Belagodu Sridhar; Neelu Farhath Abdullah Basha; Shamma Sulaiman Hasan Bin Taleth Alshemeil; Noora Adel Ahmed Aljallaf Alzaabi
Journal:  Cureus       Date:  2021-03-08

Review 4.  The Value of Electronic Health Records Since the Health Information Technology for Economic and Clinical Health Act: Systematic Review.

Authors:  Shikha Modi; Sue S Feldman
Journal:  JMIR Med Inform       Date:  2022-09-27

5.  Evaluation of drug information resources for drug-ethanol and drug-tobacco interactions.

Authors:  Robert D Beckett; Curtis D Stump; Megan A Dyer
Journal:  J Med Libr Assoc       Date:  2019-01-01
  5 in total

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