Literature DB >> 28338356

The accessory gene regulator-1 as a therapeutic target for C. difficile infections.

Charles Darkoh1,2, Herbert L DuPont1,2,3.   

Abstract

Entities:  

Keywords:  C. difficile Agr system; C. difficile pathogenesis; C. difficile quorum sensing; C. difficile virulence; accesory genes regulator system; bacterial pathogenesis

Mesh：

Substances：

Year:  2017        PMID： 28338356      PMCID： PMC5904790          DOI： 10.1080/14728222.2017.1311863

Source DB:  PubMed          Journal:  Expert Opin Ther Targets        ISSN： 1472-8222            Impact factor:   6.902


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  19 in total

Review 1.  Quorum sensing in staphylococci.

Authors:  Richard P Novick; Edward Geisinger
Journal:  Annu Rev Genet       Date:  2008       Impact factor: 16.830

2.  Transcription analysis of the genes tcdA-E of the pathogenicity locus of Clostridium difficile.

Authors:  T Hundsberger; V Braun; M Weidmann; P Leukel; M Sauerborn; C von Eichel-Streiber
Journal:  Eur J Biochem       Date:  1997-03-15

3.  Environmental response and autoregulation of Clostridium difficile TxeR, a sigma factor for toxin gene expression.

Authors:  Nagraj Mani; Dena Lyras; Lisa Barroso; Pauline Howarth; Tracy Wilkins; Julian I Rood; Abraham L Sonenshein; Bruno Dupuy
Journal:  J Bacteriol       Date:  2002-11       Impact factor: 3.490

4.  The role of toxin A and toxin B in Clostridium difficile infection.

Authors:  Sarah A Kuehne; Stephen T Cartman; John T Heap; Michelle L Kelly; Alan Cockayne; Nigel P Minton
Journal:  Nature       Date:  2010-09-15       Impact factor: 49.962

5.  Fidaxomicin versus vancomycin for infection with Clostridium difficile in Europe, Canada, and the USA: a double-blind, non-inferiority, randomised controlled trial.

Authors:  Oliver A Cornely; Derrick W Crook; Roberto Esposito; André Poirier; Michael S Somero; Karl Weiss; Pamela Sears; Sherwood Gorbach
Journal:  Lancet Infect Dis       Date:  2012-02-08       Impact factor: 25.071

Review 6.  Fecal transplantation for recurrent Clostridium difficile infection in older adults: a review.

Authors:  Kristin E Burke; John T Lamont
Journal:  J Am Geriatr Soc       Date:  2013-07-19       Impact factor: 5.562

7.  The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins.

Authors:  I Just; M Wilm; J Selzer; G Rex; C von Eichel-Streiber; M Mann; K Aktories
Journal:  J Biol Chem       Date:  1995-06-09       Impact factor: 5.157

8.  Precise manipulation of the Clostridium difficile chromosome reveals a lack of association between the tcdC genotype and toxin production.

Authors:  Stephen T Cartman; Michelle L Kelly; Daniela Heeg; John T Heap; Nigel P Minton
Journal:  Appl Environ Microbiol       Date:  2012-04-20       Impact factor: 4.792

Review 9.  Burden of Clostridium difficile on the healthcare system.

Authors:  Erik R Dubberke; Margaret A Olsen
Journal:  Clin Infect Dis       Date:  2012-08       Impact factor: 9.079

Review 10.  The Regulatory Networks That Control Clostridium difficile Toxin Synthesis.

Authors:  Isabelle Martin-Verstraete; Johann Peltier; Bruno Dupuy
Journal:  Toxins (Basel)       Date:  2016-05-14       Impact factor: 4.546
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