Literature DB >> 28333602

Bilateral Basaloid Squamous Cell Carcinoma of the Parotid Gland: A Case Report and Review of the Literature.

Alexander Rivero1, Christopher G Tang2, Barry M Rasgon3.   

Abstract

INTRODUCTION: We describe the first known case of bilateral basaloid squamous cell carcinoma of the parotid gland, and we review existing literature. CASE
PRESENTATION: A previously healthy, 70-year-old white man presented with a 2-cm enlarging mass in the tail of the right parotid gland. Magnetic resonance imaging and computed tomography showed ipsilateral pathologic adenopathy. Results of fine-needle aspiration revealed a high-grade malignancy with squamous features. The patient underwent a right total parotidectomy and modified radical neck dissection. Final pathologic findings revealed a basaloid squamous cell carcinoma. Four years after the initial resection, the patient presented with an enlarging left parotid mass. Findings of fine-needle aspiration and imaging were similar to those 4 years earlier. The patient received a left total parotidectomy and modified radical neck dissection. Postoperative radiation therapy was performed after each surgical intervention. He remains disease free at 4-year follow-up after the second mass was resected. DISCUSSION: Squamous cell carcinoma with basaloid features is a rare and aggressive type of squamous cell carcinoma. To our knowledge, this is the first case report of bilateral parotid basaloid squamous cell carcinoma.

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Mesh:

Year:  2017        PMID: 28333602      PMCID: PMC5363892          DOI: 10.7812/TPP/16-042

Source DB:  PubMed          Journal:  Perm J        ISSN: 1552-5767


  7 in total

1.  Human papillomavirus-positive basaloid squamous cell carcinomas of the upper aerodigestive tract: a distinct clinicopathologic and molecular subtype of basaloid squamous cell carcinoma.

Authors:  Rebecca D Chernock; James S Lewis; Qin Zhang; Samir K El-Mofty
Journal:  Hum Pathol       Date:  2010-03-17       Impact factor: 3.466

2.  Basaloid squamous cell carcinoma of the head and neck: location means everything.

Authors:  Valerie A Fritsch; Eric J Lentsch
Journal:  J Surg Oncol       Date:  2014-01-24       Impact factor: 3.454

3.  Basaloid squamous cell carcinoma of the head and neck is a mixed variant that can be further resolved by HPV status.

Authors:  Shanaz Begum; William H Westra
Journal:  Am J Surg Pathol       Date:  2008-07       Impact factor: 6.394

4.  Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: report of 10 cases.

Authors:  S L Wain; R Kier; R T Vollmer; E H Bossen
Journal:  Hum Pathol       Date:  1986-11       Impact factor: 3.466

5.  The CARE guidelines: consensus-based clinical case report guideline development.

Authors:  Joel J Gagnier; Gunver Kienle; Douglas G Altman; David Moher; Harold Sox; David Riley
Journal:  J Clin Epidemiol       Date:  2013-09-12       Impact factor: 6.437

6.  Basaloid squamous cell carcimoma: A rare case report with review of literature.

Authors:  Bn Shivakumar; Bishwajeet Dash; Anshuta Sahu; Barakha Nayak
Journal:  J Oral Maxillofac Pathol       Date:  2014-05

Review 7.  Histopathologic risk factors in oral and oropharyngeal squamous cell carcinoma variants: an update with special reference to HPV-related carcinomas.

Authors:  Samir K El-Mofty
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2014-07-01
  7 in total
  1 in total

1.  Primary basaloid squamous cell carcinoma of the parotid gland mimicking metastasis of basal cell carcinoma of the contralateral periorbital region: case report.

Authors:  Krzysztof Gąsiorowski; Dariusz Adamek; Jan Zapała; Jakub Bargiel; Michał Gontarz; Anna Hulacka; Tomasz Marecik; Paweł Szczurowski; Grażyna Wyszyńska-Pawelec
Journal:  Gland Surg       Date:  2022-01
  1 in total

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