Literature DB >> 28331018

Strongyloides hyperinfection syndrome in an immunocompetent host resulting in bandemia and death.

Aung Myint1, Courtney Chapman2, Isabel Almira-Suarez2, Nupur Mehta1.   

Abstract

Strongyloides stercoralis infection is usually asymptomatic but can result in a hyperinfection syndrome, most commonly triggered by acquired or iatrogenic immunosuppression. Here, we present a case of a man aged 60 years originally from a strongyloides endemic area with a medical history of alcohol abuse who presents with strongyloides hyperinfection syndrome (SHS) complicated by partial small bowel obstruction, pulmonary haemorrhage, large bandemia without eosinophilia and cardiac arrest resulting in death. This case is notable for the presence of bandemia and absence of eosinophilia, lack of historical risk factors for hyperinfection, specifically corticosteroid immunosuppressants, and dramatic decline in clinical status which ultimately resulted in the patient's death. Clinicians should suspect SHS in immunocompetent patients who are from an endemic area and who have persistent gastrointestinal and/or pulmonary manifestations in the absence of a clear cause. 2017 BMJ Publishing Group Ltd.

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Year:  2017        PMID: 28331018      PMCID: PMC5372183          DOI: 10.1136/bcr-2016-217911

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  3 in total

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Authors:  Samira Jeimy; Kathryn McRae; Reena Pattani
Journal:  CMAJ       Date:  2018-07-09       Impact factor: 8.262

2.  Pulmonary Hyperinfection with Strongyloides stercoralis in an Immunocompetent Patient.

Authors:  Sadik Mohammed; Pradeep Bhatia; Swati Chhabra; Sunit Kumar Gupta; Rakesh Kumar
Journal:  Indian J Crit Care Med       Date:  2019-10

3.  Comparison of Trials Using Ivermectin for COVID-19 Between Regions With High and Low Prevalence of Strongyloidiasis: A Meta-analysis.

Authors:  Avi Bitterman; Caitlin Pestana Martins; Ahuva Cices; Makarand Prasad Nadendla
Journal:  JAMA Netw Open       Date:  2022-03-01
  3 in total

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