Roberto Carlos Castrejón-Pérez1,2, Aida Jiménez-Corona3, Eduardo Bernabé4, Antonio R Villa-Romero5, Elise Arrivé6, Jean-François Dartigues6, Luis Miguel Gutiérrez-Robledo7, S Aída Borges-Yáñez8. 1. National Institute of Geriatrics, National Institutes of Health, Mexico. 2. Department of Geriatric Clinical and Epidemiological Research, National Institute of Geriatrics, National institutes of Health, Mexico. 3. Department of Ocular Epidemiology, Ophthalmic Institute "Conde de Valenciana,"Mexico. 4. Unit of Dental Public Health, King's College London Dental Institute, UK. 5. Department of Research Methodology, School of Medicine, National Autonomous University of Mexico, México. 6. Department of Epidemiology, Public Health and Development, Inserm U 897, Université de Bordeaux II, France. 7. General Direction, National Institute of Geriatrics, National Institutes of Health, Mexico. 8. Department of Dental Public Health, Graduate and Research Division, Dental School, National Autonomous University of Mexico, Mexico.
Abstract
BACKGROUND: Poor oral health has been associated with some components of frailty. The objective of this study was to identify the association between clinical measures of oral health and the incidence of frailty among community-dwelling older adults aged 70 or older in Mexico City. METHODS: A 3-year cohort study with a probabilistic representative sample of home-dwelling elders of one district of Mexico City was performed. Baseline and follow-up interview and oral clinical evaluations were carried out by standardized examiners in participants' homes. Dependent variable was incident frailty defined according to the frailty phenotype. Independent variables were the utilization of dental services, the presence of xerostomia, the number of natural teeth, use of removable dental prostheses, presence of severe periodontitis, and presence of root remnants. Sociodemographic, behavioral, and health measures were included as confounders. The association between oral health conditions and incident frailty was modeled using Poisson regression models with robust variance estimators. The models were adjusted for confounders and interactions. RESULTS: We identified a 14.8% cumulative incidence of frailty. Each additional tooth was associated with a lower probability of developing frailty by 5.0% (risk ratio = 0.90; 95% CI 1.02-1.10). The 3-year risk ratio of developing frailty was 2.13 times higher (95% CI 1.01-4.50) among participants having severe periodontitis. CONCLUSIONS: The number of teeth and the presence of severe periodontitis are associated with the development of frailty after controlling for confounders. Further studies are needed on this topic.
BACKGROUND: Poor oral health has been associated with some components of frailty. The objective of this study was to identify the association between clinical measures of oral health and the incidence of frailty among community-dwelling older adults aged 70 or older in Mexico City. METHODS: A 3-year cohort study with a probabilistic representative sample of home-dwelling elders of one district of Mexico City was performed. Baseline and follow-up interview and oral clinical evaluations were carried out by standardized examiners in participants' homes. Dependent variable was incident frailty defined according to the frailty phenotype. Independent variables were the utilization of dental services, the presence of xerostomia, the number of natural teeth, use of removable dental prostheses, presence of severe periodontitis, and presence of root remnants. Sociodemographic, behavioral, and health measures were included as confounders. The association between oral health conditions and incident frailty was modeled using Poisson regression models with robust variance estimators. The models were adjusted for confounders and interactions. RESULTS: We identified a 14.8% cumulative incidence of frailty. Each additional tooth was associated with a lower probability of developing frailty by 5.0% (risk ratio = 0.90; 95% CI 1.02-1.10). The 3-year risk ratio of developing frailty was 2.13 times higher (95% CI 1.01-4.50) among participants having severe periodontitis. CONCLUSIONS: The number of teeth and the presence of severe periodontitis are associated with the development of frailty after controlling for confounders. Further studies are needed on this topic.
Authors: Vittorio Dibello; Frank Lobbezoo; Madia Lozupone; Rodolfo Sardone; Andrea Ballini; Giuseppe Berardino; Anita Mollica; Hélio José Coelho-Júnior; Giovanni De Pergola; Roberta Stallone; Antonio Dibello; Antonio Daniele; Massimo Petruzzi; Filippo Santarcangelo; Vincenzo Solfrizzi; Daniele Manfredini; Francesco Panza Journal: Geroscience Date: 2022-10-15 Impact factor: 7.581
Authors: Sheena E Ramsay; Efstathios Papachristou; Richard G Watt; Georgios Tsakos; Lucy T Lennon; A Olia Papacosta; Paula Moynihan; Avan A Sayer; Peter H Whincup; S Goya Wannamethee Journal: J Am Geriatr Soc Date: 2017-12-20 Impact factor: 5.562
Authors: Richard Ofori-Asenso; Ken L Chin; Mohsen Mazidi; Ella Zomer; Jenni Ilomaki; Andrew R Zullo; Danijela Gasevic; Zanfina Ademi; Maarit J Korhonen; Dina LoGiudice; J Simon Bell; Danny Liew Journal: JAMA Netw Open Date: 2019-08-02