Literature DB >> 28329498

Bullous pemphigoid of infancy - report and review of infantile and pediatric bullous pemphigoid.

Bárbara R Ferreira1, Ana S Vaz, Leonor Ramos, José P Reis, Margarida Gonçalo.   

Abstract

A 4-month-old infant was observed with an acute itchy bullous dermatosis, predominantly involving the extremities, which revealed a dermal infiltrate rich in eosinophils, C3 deposits at the dermalepidermal junction, and circulating antibodies to BP180 antigen, confirming the diagnosis of bullous pemphigoid. He was initially treated with deflazacort 1 mg/kg/day, further increased to 2 mg/ kg/day, followed by reduction over seven weeks with complete clinical resolution within this period. We discuss epidemiology, etiology, relationship with vaccination, clinical features, and treatment of thisrelatively rare bullous dermatosis in the pediatric age.

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Year:  2017        PMID: 28329498

Source DB:  PubMed          Journal:  Dermatol Online J        ISSN: 1087-2108


  2 in total

Review 1.  Clarithromycin as a steroid sparing agent for the management of infantile bullous pemphigoid.

Authors:  Simon Tso; Gabriela Petrof; Simon Unter; Frances Humphreys
Journal:  BMJ Case Rep       Date:  2018-01-26

2.  Two infants with blistering rashes originating on acral sites as a presenting sign of infantile bullous pemphigoid.

Authors:  Brent Folsom; Tom Raisanen; Milad Eshaq
Journal:  JAAD Case Rep       Date:  2020-04-18
  2 in total

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