Literature DB >> 28327724

Reversible crystal-to-crystal chiral resolution: making/breaking non-bonding SO interactions.

R Alex Mayo1, David J Sullivan1, Travis A P Fillion1, Stefan W Kycia2, Dmitriy V Soldatov1, Kathryn E Preuss1.   

Abstract

An achiral organic molecule adopts a chiral conformation, crystallizing in two morphologies: a racemic form, stable <70 °C, and a homochiral form, stable ≥70 °C. Upon seeding, crystal-to-crystal phase transitions occur reversibly between the racemic and chiral forms. Liquid-to-solid chiral crystallization is observed >90% of the time from the melt.

Year:  2017        PMID: 28327724     DOI: 10.1039/c7cc00907k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Experimental and Computational Structural Studies of 2,3,5-Trisubstituted and 1,2,3,5-Tetrasubstituted Indoles as Non-Competitive Antagonists of GluK1/GluK2 Receptors.

Authors:  Agata Bartyzel; Agnieszka A Kaczor; Ghodrat Mahmoudi; Ardavan Masoudiasl; Tomasz M Wróbel; Monika Pitucha; Dariusz Matosiuk
Journal:  Molecules       Date:  2022-04-12       Impact factor: 4.927

  1 in total

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