Literature DB >> 28323290

Incidence and risk factors for delirium development in ICU patients - a prospective observational study.

Marcela Kanova1,2,3, Peter Sklienka2,3, Kula Roman2,3, Michal Burda4, Jana Janoutova1.   

Abstract

BACKGROUND AND AIMS: Delirium is an acute brain dysfunction and a frequent complication in critically ill patients. When present it significantly worsens the prognosis of patients. The aim of this study was to evaluate the incidence of delirium and risk factors for delirium in a mixed group of trauma, medical and surgical ICU patients.
METHODS: A prospective observational study was conducted in one of the six-bed Intensive Care Units of the University Hospital Ostrava in the Czech Republic during a 12-month period. We evaluated the incidence of delirium and its predisposing and precipitating risk factors. All patients were assessed daily using the Confusion Assessment Method for the ICU (CAM-ICU). RESULTS AND
CONCLUSIONS: Of the total of 332 patients with a median APACHE II (the Acute Physiology and Chronic Health Evaluation) score of 12, who were evaluated for delirium, 48 could not be assessed using CAM-ICU (47 due to prolonged coma, 1 due to language barriers). The incidence of delirium was 26.1%, with trauma and medical patients being more likely to develop delirium than surgical patients. Risk of delirium was significantly associated with age ≥ 65 years, and alcohol abuse in their anamnesis, with APACHE II score on admission, and with the use of sedatives and/or vasopressors. Delirious patients who remained in the ICU for a prolonged period showed a greater need for ventilator support and had a greater ICU-mortality.

Entities:  

Keywords:  CAM-ICU diagnostic test; artificial ventilation; critically ill patients; delirium; predisposing and precipitating risk factors

Mesh:

Year:  2017        PMID: 28323290     DOI: 10.5507/bp.2017.004

Source DB:  PubMed          Journal:  Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub        ISSN: 1213-8118            Impact factor:   1.245


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7.  Prevalence and risk factors related to haloperidol use for delirium in adult intensive care patients: the multinational AID-ICU inception cohort study.

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9.  ICU Delirium-Prediction Models: A Systematic Review.

Authors:  Matthew M Ruppert; Jessica Lipori; Sandip Patel; Elizabeth Ingersent; Julie Cupka; Tezcan Ozrazgat-Baslanti; Tyler Loftus; Parisa Rashidi; Azra Bihorac
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10.  Incidence, risk factors, and cumulative risk of delirium among ICU patients: A case-control study.

Authors:  Yanbin Pan; Jianlong Yan; Zhixia Jiang; Jianying Luo; Jingjing Zhang; Kaihan Yang
Journal:  Int J Nurs Sci       Date:  2019-06-02
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