J N Baldwin1, M J McKay2, M Simic3, C E Hiller2, N Moloney4, E J Nightingale2, J Burns5. 1. Arthritis and Musculoskeletal Research Group, Faculty of Health Sciences, University of Sydney, Australia. Electronic address: jennifer.baldwin@sydney.edu.au. 2. Arthritis and Musculoskeletal Research Group, Faculty of Health Sciences, University of Sydney, Australia. 3. Arthritis and Musculoskeletal Research Group, University of Sydney, Australia. 4. Arthritis and Musculoskeletal Research Group, Faculty of Health Sciences, University of Sydney, Australia; Department of Health Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia. 5. Arthritis and Musculoskeletal Research Group, Faculty of Health Sciences, University of Sydney, Australia; Paediatric Gait Analysis Service of New South Wales, Sydney Children's Hospitals Network (Randwick and Westmead), Australia.
Abstract
OBJECTIVE: To develop normative reference data for the Knee injury and Osteoarthritis Outcome Score (KOOS) and KOOS-Child, as well as investigate socio-demographic, psychological and physical factors associated with knee pain and disability among healthy adults. METHOD: The KOOS or KOOS-Child (each containing five subscales) was administered to participants aged 8-101 years within the 1000 Norms Project, an observational study of 1000 self-reported healthy individuals. Self-efficacy, physical activity, body mass index (BMI), lower limb alignment, knee frontal plane projection angle (FPPA), knee range of motion (ROM), knee and hip strength, six-minute walk, 30-second chair stand and timed up and down stairs tests were collected. KOOS data were dichotomised using established cut-off scores and logistic regression analyses were conducted for each subscale. RESULTS: Socio-demographic characteristics were similar to the Australian population. Normative reference data were generated for children (8-17 years) and adults (18-101 years). Female adults were up to twice as likely to report knee pain, symptoms and sport/recreation (Sport/Rec) limitations compared to males (P < .05). Older age, lower self-efficacy, greater BMI, varus lower limb alignment, lower knee flexion ROM and lower hip external rotation (ER) strength were independently associated with knee pain and disability among adults. CONCLUSIONS: Age- and gender-stratified reference data for the KOOS and KOOS-Child have been developed to guide interpretation of results in practice and research for individuals with knee disorders. Psychological and physical factors are linked with self-reported knee pain/disability among adults, and longitudinal studies to investigate causation are required.
OBJECTIVE: To develop normative reference data for the Knee injury and Osteoarthritis Outcome Score (KOOS) and KOOS-Child, as well as investigate socio-demographic, psychological and physical factors associated with knee pain and disability among healthy adults. METHOD: The KOOS or KOOS-Child (each containing five subscales) was administered to participants aged 8-101 years within the 1000 Norms Project, an observational study of 1000 self-reported healthy individuals. Self-efficacy, physical activity, body mass index (BMI), lower limb alignment, knee frontal plane projection angle (FPPA), knee range of motion (ROM), knee and hip strength, six-minute walk, 30-second chair stand and timed up and down stairs tests were collected. KOOS data were dichotomised using established cut-off scores and logistic regression analyses were conducted for each subscale. RESULTS: Socio-demographic characteristics were similar to the Australian population. Normative reference data were generated for children (8-17 years) and adults (18-101 years). Female adults were up to twice as likely to report knee pain, symptoms and sport/recreation (Sport/Rec) limitations compared to males (P < .05). Older age, lower self-efficacy, greater BMI, varus lower limb alignment, lower knee flexion ROM and lower hip external rotation (ER) strength were independently associated with knee pain and disability among adults. CONCLUSIONS: Age- and gender-stratified reference data for the KOOS and KOOS-Child have been developed to guide interpretation of results in practice and research for individuals with knee disorders. Psychological and physical factors are linked with self-reported knee pain/disability among adults, and longitudinal studies to investigate causation are required.
Authors: Matthew C Bessette; Robert W Westermann; Alan Davis; Lutul Farrow; Mia S Hagen; Anthony Miniaci; Robert Nickodem; Richard Parker; James Rosneck; Paul Saluan; Kurt P Spindler; Kim Stearns; Morgan H Jones Journal: Orthop J Sports Med Date: 2019-05-15
Authors: Weihua Meng; Mark J Adams; Colin N A Palmer; Jingchunzi Shi; Adam Auton; Kathleen A Ryan; Joanne M Jordan; Braxton D Mitchell; Rebecca D Jackson; Michelle S Yau; Andrew M McIntosh; Blair H Smith Journal: Commun Biol Date: 2019-08-28
Authors: Eleni Zengini; Konstantinos Hatzikotoulas; Ioanna Tachmazidou; Julia Steinberg; Fernando P Hartwig; Lorraine Southam; Sophie Hackinger; Cindy G Boer; Unnur Styrkarsdottir; Arthur Gilly; Daniel Suveges; Britt Killian; Thorvaldur Ingvarsson; Helgi Jonsson; George C Babis; Andrew McCaskie; Andre G Uitterlinden; Joyce B J van Meurs; Unnur Thorsteinsdottir; Kari Stefansson; George Davey Smith; Jeremy M Wilkinson; Eleftheria Zeggini Journal: Nat Genet Date: 2018-03-20 Impact factor: 38.330