Literature DB >> 28322457

Declining antibody levels after hepatitis B vaccination in Down syndrome: A need for booster vaccination?

Noortje B Eijsvoogel1, Mirjam I Hollegien1, Vinus L A Bok2, Arda G Derksen Lubsen3, Felix P J Dikken4, Sander A C A P Leenders5, Arjan Pijning6, Erica Post7, Marek Wojciechowski8, Mirrian Hilbink9, Esther de Vries1,10.   

Abstract

We determined the anti-HBs titer in 227 children of all ages with Down syndrome (DS). Only 48.1% (95%CI: 35.1-61.3) of the DS children aged 7-10 years and 31.9% (95%CI: 22.1-43.6) of the DS children aged >10 years had a protective anti-HBs titer (≥10 IU/L). The geometric mean anti-HBs titer was significantly lower in the DS children; this suggests booster vaccination for HBV may be needed.
© 2017 Wiley Periodicals, Inc.

Entities:  

Keywords:  Down syndrome; hepatitis B vaccination; hepatitis B virus

Mesh：

Substances：

Year:  2017        PMID： 28322457     DOI： 10.1002/jmv.24813

Source DB:  PubMed          Journal:  J Med Virol        ISSN： 0146-6615            Impact factor:   2.327


  5 in total

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Review 5.  Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome.

Authors:  Tomer Illouz; Arya Biragyn; Maria Florencia Iulita; Lisi Flores-Aguilar; Mara Dierssen; Ilario De Toma; Stylianos E Antonarakis; Eugene Yu; Yann Herault; Marie-Claude Potier; Alexandra Botté; Randall Roper; Benjamin Sredni; Jacqueline London; William Mobley; Andre Strydom; Eitan Okun
Journal:  Front Immunol       Date:  2021-06-25       Impact factor: 7.561
  5 in total

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