To the Editor,We thank the authors et al. (1) for their important comments to our paper entitled “Use of strain and strain rate echocardiographic imaging to predict the progression of mitral stenosis: a 5-year follow-up study” published in the Anatolian Journal of Cardiology 2016; 16: 772-7.As you mentioned, we have not provided some data in the text, for example the volume measurements. There is no data regarding the volume measurements in the text because we aimed to compare routine measurements taken in our laboratory. We routinely do not take volume measurements; therefore, we only provided information regarding the dimensions of the chambers. Similarly, we did not mention the degree of mitral regurgitation because we only included patients with isolated mitral stenosis. No patients with moderate or severe MR were included in our study; therefore, we did not mention this data in the text.You have mentioned that there was no control group and GLS/GLSR was not measured at the end of the study. However, we have mentioned this as a study limitation. The use of GLS/GLSR as a predictor of MS progression can be helpful to decide the frequency of control visits and to plan optimal management of the patient. Our study results are positive, but as you have mentioned, we need larger prospective studies for more clinical use.