Mangsuo Zhao1, Bingxin Shi1, Tuoyu Chen2, Yuqi Zhang2, Tongchao Geng1, Liyan Qiao1, Mingjie Zhang3, Le He4, Huancong Zuo5, Guihuai Wang6. 1. Department of Neurology, Yuquan Hospital, Clinical Neuroscience Institute, Medical Center, Tsinghua University, Beijing 100040, PR China. 2. Department of Neurosurgery, Yuquan Hospital, Clinical Neuroscience Institute, Medical Center, Tsinghua University, Beijing 100040, PR China. 3. Department of Neurology, PLA General Hospital, Beijing 100853, PR China. 4. Center for Biomedical Imaging Research, Tsinghua University, Beijing 100084, PR China. 5. Department of Neurosurgery, Yuquan Hospital, Clinical Neuroscience Institute, Medical Center, Tsinghua University, Beijing 100040, PR China. Electronic address: zuohuancong@163.com. 6. Department of Neurosurgery, Changgung Hospital, Medical Center, Tsinghua University, Beijing 102218, PR China. Electronic address: youngneurosurgeon@163.com.
Abstract
OBJECTIVE: To evaluate the diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) features of cervical spinal cord astrocytoma. METHODS: Eleven patients with cervical spinal cord astrocytomas and 10 healthy volunteers were recruited in this study. Conventional magnetic resonance imaging (MRI) and axial DTI were performed on a 3.0T MRI system. Apparent diffusion coefficient (ADC), fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD) values for the lesions were measured. DTT was performed using the principal diffusion direction method. RESULTS: ADC values of the lesions and the normal-appearing tissue around the tumour (NATAT) on T2-weighted imaging (T2WI) increased. The ADC values of the lesions were higher. The FA values of the lesions and the NATAT decreased significantly, with the lesions having lower FA values. The RD value (1.36±0.49) of the tumours was significantly higher than those found in the healthy controls, but similar for the AD value (1.84±0.56). There were no differences in ADC or FA values between lesions and NATAT in McCormick Type I vs. Type II patients. Based on the DTT, 7 patients with solid mass tumours were classified as Type I. One patient with a solid mass, 2 patients with cystic degeneration inside the lesions, and 1 patient with a cyst around the mass were classified as Type II. CONCLUSIONS: FA values of the cervical spinal cord astrocytoma decreased, but the ADC values increased. DTI was sensitive for the evaluation of pathological changes that could not be visualized on T2WI. Our preliminary study indicates that DTT can be used to guide operation planning, and that axial images of DTT may be more valuable.
OBJECTIVE: To evaluate the diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) features of cervical spinal cord astrocytoma. METHODS: Eleven patients with cervical spinal cord astrocytomas and 10 healthy volunteers were recruited in this study. Conventional magnetic resonance imaging (MRI) and axial DTI were performed on a 3.0T MRI system. Apparent diffusion coefficient (ADC), fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD) values for the lesions were measured. DTT was performed using the principal diffusion direction method. RESULTS: ADC values of the lesions and the normal-appearing tissue around the tumour (NATAT) on T2-weighted imaging (T2WI) increased. The ADC values of the lesions were higher. The FA values of the lesions and the NATAT decreased significantly, with the lesions having lower FA values. The RD value (1.36±0.49) of the tumours was significantly higher than those found in the healthy controls, but similar for the AD value (1.84±0.56). There were no differences in ADC or FA values between lesions and NATAT in McCormick Type I vs. Type IIpatients. Based on the DTT, 7 patients with solid mass tumours were classified as Type I. One patient with a solid mass, 2 patients with cystic degeneration inside the lesions, and 1 patient with a cyst around the mass were classified as Type II. CONCLUSIONS: FA values of the cervical spinal cord astrocytoma decreased, but the ADC values increased. DTI was sensitive for the evaluation of pathological changes that could not be visualized on T2WI. Our preliminary study indicates that DTT can be used to guide operation planning, and that axial images of DTT may be more valuable.
Authors: Semih Kivanc Olguner; Ali Arslan; Vedat Açık; İsmail İstemen; Mehmet Can; Yurdal Gezercan; Ali İhsan Ökten Journal: Front Oncol Date: 2021-01-28 Impact factor: 6.244
Authors: Edyta Maj; Barbara Szemplińska; Wojciech Szeszkowski; Marek Prokopienko; Andrzej Cieszanowski; Andrzej Marchel; Olgierd Rowiński Journal: Clin Neuroradiol Date: 2019-11-21 Impact factor: 3.649