Literature DB >> 28318941

Expanding the tetrahydroquinoline pharmacophore.

Navya Goli1, Prathama S Mainkar2, Sudha Sravanti Kotapalli3, Tejaswini K3, Ramesh Ummanni4, Srivari Chandrasekhar5.   

Abstract

Tetrahydroquinoline is a privileged scaffold with a large number of biological applications. The tetrahydroquinoline pharmacophore has been expanded to yield 34 compounds. Biological screening of these compounds led to the identification of tetrahydroquinoline as neurotropic agents not reported earlier.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Keywords:  Neurotropic agents; Povarov reaction; Tetrahydroquinoline

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Year:  2017        PMID: 28318941     DOI: 10.1016/j.bmcl.2017.02.077

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  A thiadiazolopyridine-functionalized Zr(iv)-based metal-organic framework for enhanced photocatalytic synthesis of tetrahydroquinolines under visible light.

Authors:  Changyun Li; He Zhang; Xuefei Wang; Qiu-Yan Li; Xinsheng Zhao; Xiao-Jun Wang
Journal:  RSC Adv       Date:  2022-01-10       Impact factor: 3.361

2.  Synthesis of Novel Spiro-Tetrahydroquinoline Derivatives and Evaluation of Their Pharmacological Effects on Wound Healing.

Authors:  Yan-Cheng Liou; Yan-An Lin; Ke Wang; Juan-Cheng Yang; Yeong-Jiunn Jang; Wenwei Lin; Yang-Chang Wu
Journal:  Int J Mol Sci       Date:  2021-06-10       Impact factor: 5.923

  2 in total

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