Dinesh Visva Gunasekeran1,2, Bhaskar Gupta2,3, Joao Cardoso2, Carlos E Pavesio2,4, Rupesh Agrawal1,2,4. 1. a National Healthcare Group Eye Institute, Tan Tock Seng Hospital , Singapore , Singapore. 2. b Moorfields Eye Hospital, NHS Foundation Trust , London , UK. 3. c Royal Berkshire Hospital, NHS Foundation Trust , Reading , UK. 4. d Biomedical Research Centre, UCL Institute of Ophthalmology , London , UK.
Abstract
PURPOSE: To describe the visual morbidity associated with intraocular tuberculosis (TB) and to report ocular complications of intraocular TB. METHODS: Retrospective cohort study of patients diagnosed with intraocular TB at a tertiary referral eye care hospital in central London. Data on baseline and final best-corrected visual acuity (BCVA) along with ocular complications were collected and analyzed. RESULTS: In total, 354 patients with intraocular TB were included in this study. Mean age was 48.45 years (range 19-94) and follow-up was 22.56 ± 7.44 (range 6-30) months post cessation of therapy. Blindness as defined by the World Health Organization was reported in 11 (3.11%) patients at baseline and 13 (3.67%) patients at follow-up. The most common ocular complications were cystoid macular edema (n = 107, 30.5%) and glaucoma (n = 99, 28.12%). CONCLUSION: Intraocular TB can be associated with significant ocular morbidity. Early recognition, treatment, and regular follow-up of this complex disease may help to reduce visual morbidity and ocular complications.
PURPOSE: To describe the visual morbidity associated with intraocular tuberculosis (TB) and to report ocular complications of intraocular TB. METHODS: Retrospective cohort study of patients diagnosed with intraocular TB at a tertiary referral eye care hospital in central London. Data on baseline and final best-corrected visual acuity (BCVA) along with ocular complications were collected and analyzed. RESULTS: In total, 354 patients with intraocular TB were included in this study. Mean age was 48.45 years (range 19-94) and follow-up was 22.56 ± 7.44 (range 6-30) months post cessation of therapy. Blindness as defined by the World Health Organization was reported in 11 (3.11%) patients at baseline and 13 (3.67%) patients at follow-up. The most common ocular complications were cystoid macular edema (n = 107, 30.5%) and glaucoma (n = 99, 28.12%). CONCLUSION: Intraocular TB can be associated with significant ocular morbidity. Early recognition, treatment, and regular follow-up of this complex disease may help to reduce visual morbidity and ocular complications.
Authors: Erika Marie Damato; Sarah Dawson; Xiaoxuan Liu; Chandoshi Mukherjee; John Horsburgh; Alastair K Denniston; Edward Moran; Martin Dedicoat; Philip Ian Murray Journal: J Ophthalmic Inflamm Infect Date: 2017-12-04
Authors: M La Cava; A Bruscolini; M Sacchetti; M P Pirraglia; A Moramarco; M Marenco; G Iaiani; G Covelli; T Rizzo; I Abicca; A Lambiase Journal: J Ophthalmol Date: 2020-03-14 Impact factor: 1.909