Literature DB >> 2831654

Characteristics of the minor group receptor of human rhinoviruses.

H Mischak1, C Neubauer, E Kuechler, D Blaas.   

Abstract

The receptor for the minor group of human rhinoviruses was solubilized from HeLa cell membranes with various detergents. Virus binding activity was determined in a filter binding assay using 35S-labeled human rhinovirus 2 (HRV2) as a probe. The receptor protein was enriched on Lens culinaris lectin columns and the active fractions were further purified by gel permeation and anion exchange chromatography. The receptor has an apparent molecular weight of 450 kDa in the presence of detergent. The binding activity is sensitive to trypsin, sulfhydryl modifying agents, but insensitive to neuraminidase. Divalent cations are essential for virus binding.

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Year:  1988        PMID： 2831654     DOI： 10.1016/0042-6822(88)90229-2

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  6 in total

Review 1.  Strategies for the identification of icosahedral virus receptors.

Authors:  D M Bass; H B Greenberg
Journal:  J Clin Invest       Date:  1992-01       Impact factor: 14.808

2.  Identification of two surface proteins from C6/36 cells that bind dengue type 4 virus.

Authors:  J S Salas-Benito; R M del Angel
Journal:  J Virol       Date:  1997-10       Impact factor: 5.103

3.  A mutation in the first ligand-binding repeat of the human very-low-density lipoprotein receptor results in high-affinity binding of the single V1 module to human rhinovirus 2.

Authors:  Stephane Nizet; Juergen Wruss; Nathalie Landstetter; Luc Snyers; Dieter Blaas
Journal:  J Virol       Date:  2005-12       Impact factor: 5.103

4.  The minor receptor group of human rhinovirus (HRV) includes HRV23 and HRV25, but the presence of a lysine in the VP1 HI loop is not sufficient for receptor binding.

Authors:  Marketa Vlasak; Merja Roivainen; Manuela Reithmayer; Irene Goesler; Pia Laine; Luc Snyers; Tapani Hovi; Dieter Blaas
Journal:  J Virol       Date:  2005-06       Impact factor: 5.103

5.  Members of the low density lipoprotein receptor family mediate cell entry of a minor-group common cold virus.

Authors:  F Hofer; M Gruenberger; H Kowalski; H Machat; M Huettinger; E Kuechler; D Blaas
Journal:  Proc Natl Acad Sci U S A       Date:  1994-03-01       Impact factor: 11.205

6.  Study of the parameters of binding of R 61837 to human rhinovirus 9 and immunobiochemical evidence of capsid-stabilizing activity of the compound.

Authors:  M Moeremans; M De Raeymaeker; G Daneels; M De Brabander; F Aerts; C Janssen; K Andries
Journal:  Antimicrob Agents Chemother       Date:  1992-02       Impact factor: 5.191
  6 in total

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