Literature DB >> 28315737

Botulinum toxin as an adjunct to monocular recession-resection surgery for large-angle sensory strabismus.

Betül Tuğcu1, Eda Sönmezay2, Fadime Nuhoğlu2, Hakan Özdemir2, Seyhan Bahar Özkan3.   

Abstract

PURPOSE: To evaluate the result of using intraoperative botulinum toxin A (BTA) as an adjunct to monocular recession-resection surgery in the management of large-angle sensory strabismus.
METHODS: The medical records of patients diagnosed with sensory strabismus with constant large-angle strabismus were reviewed retrospectively to identify those who underwent monocular recession-resection surgery combined with 5 units of BTA injection into the recessed muscle of the nonfixating eye. Surgical outcome was considered successful if the final deviation was within the range of 0Δ-10Δ.
RESULTS: A total of 13 patients (mean age, 31.04 ± 18.5 years) were included, 8 with exotropia and 5 with esotropia. The mean follow-up period was 52.77 ± 10.9 months. The mean preoperative deviation was 66Δ ± 16Δ in the esodeviation group and 56Δ ± 5Δ in the exodeviation group. The final postoperative mean deviation was 6Δ ± 7Δ in the esodeviation group and 6Δ ± 8Δ in the exodeviation group. There were 7 patients (87.5%) with final deviation of ≤10Δ in the exodeviaton group and 4 (80%) in the esodeviation group.
CONCLUSIONS: Adjunctive usage of BTA with conventional surgery appears to enhance surgical outcomes by increasing the amount of expected correction. The combined use of BTA with monocular recession-resection rectus muscle surgery may be a good alternative in the treatment of large-angle sensory strabismus with the advantage of less risk of potential complications compared to supramaximal surgery or surgery in the "good" eye.
Copyright © 2017 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.

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Year:  2017        PMID: 28315737     DOI: 10.1016/j.jaapos.2017.03.008

Source DB:  PubMed          Journal:  J AAPOS        ISSN: 1091-8531            Impact factor:   1.220


  3 in total

1.  Three horizontal muscle surgery for large-angle esotropia: success rate and dose-effect ratio.

Authors:  Reza Nabie; Vahideh Manouchehri; Saba Salehpour; Banafsheh Kharrazi Ghadim; Erfan Bahramani
Journal:  Int J Ophthalmol       Date:  2020-04-18       Impact factor: 1.779

2.  Botulinum toxin augmented bilateral lateral rectus recession versus three muscles surgery in large-angle intermittent exotropia.

Authors:  Hala Kamal Mattout; Sameh Mosaad Fouda; Wael M El-Haig
Journal:  Int J Ophthalmol       Date:  2022-10-18       Impact factor: 1.645

3.  Supramaximal Recession and Resection Surgery in Large-Angle Strabismus: Outcomes of Large Interventional Case Series Exotropia and Esotropia.

Authors:  Mohammad Reza Talebnejad; Mohammad Karim Johari; Mohammad Reza Khalili; Mousa Zare
Journal:  J Curr Ophthalmol       Date:  2020-03-23
  3 in total

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