Literature DB >> 28315719

Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 100 Luo infants from the Boro area of Nyanza Province, Kenya.

Cecilia S Lindestam Arlehamn1, Richard Copin2, Shay Leary3, Steven J Mack4, Elizabeth Phillips5, Simon Mallal5, Alessandro Sette1, Gretta Blatner6, Heather Siefers6, Joel D Ernst7.   

Abstract

One hundred healthy infants enrolled as controls in a tuberculosis vaccine study in Nyanza Province, Kenya provided anonymized samples for DNA sequence-based typing at the HLA-A, -B, -C, -DPB1, -DQA1, -DQB1, -DRB1, and -DRB3/4/5 loci. The purpose of the study was to characterize allele frequencies in the local population, to support studies of T cell immunity against pathogens, including Mycobacterium tuberculosis. There are no detectable deviations from Hardy Weinberg proportions for the HLA-B, -C, -DRB1, -DPB1, -DQA1 and -DQB1 loci. A minor deviation was detected at the HLA-A locus due to an excess of HLA-A*02:02, 29:02, 30:02, and 68:02 homozygotes. The genotype data are available in the Allele Frequencies Net Database under identifier 3393.
Copyright © 2017. Published by Elsevier Inc.

Entities:  

Keywords:  HLA alleles; Kenya; Luo

Mesh：

Substances：

Year:  2017        PMID： 28315719      PMCID： PMC5519768          DOI： 10.1016/j.humimm.2017.03.007

Source DB:  PubMed          Journal:  Hum Immunol        ISSN： 0198-8859            Impact factor:   2.850


  5 in total

1.  PyPop update--a software pipeline for large-scale multilocus population genomics.

Authors:  A K Lancaster; R M Single; O D Solberg; M P Nelson; G Thomson
Journal:  Tissue Antigens       Date:  2007-04

2.  Next-generation sequencing for HLA typing of class I loci.

Authors:  Rachel L Erlich; Xiaoming Jia; Scott Anderson; Eric Banks; Xiaojiang Gao; Mary Carrington; Namrata Gupta; Mark A DePristo; Matthew R Henn; Niall J Lennon; Paul I W de Bakker
Journal:  BMC Genomics       Date:  2011-01-18       Impact factor: 3.969

3.  Bridging ImmunoGenomic Data Analysis Workflow Gaps (BIGDAWG): An integrated case-control analysis pipeline.

Authors:  Jill A Hollenbach; Steven J Mack; Derek J Pappas; Wesley Marin
Journal:  Hum Immunol       Date:  2015-12-18       Impact factor: 2.850

4.  Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.

Authors:  Faviel F González-Galarza; Louise Y C Takeshita; Eduardo J M Santos; Felicity Kempson; Maria Helena Thomaz Maia; Andrea Luciana Soares da Silva; André Luiz Teles e Silva; Gurpreet S Ghattaoraya; Ana Alfirevic; Andrew R Jones; Derek Middleton
Journal:  Nucleic Acids Res       Date:  2014-11-20       Impact factor: 19.160

5.  The IPD and IMGT/HLA database: allele variant databases.

Authors:  James Robinson; Jason A Halliwell; James D Hayhurst; Paul Flicek; Peter Parham; Steven G E Marsh
Journal:  Nucleic Acids Res       Date:  2014-11-20       Impact factor: 16.971
  5 in total
  2 in total

1.  High Resolution HLA ∼A, ∼B, ∼C, ∼DRB1, ∼DQA1, and ∼DQB1 Diversity in South African Populations.

Authors:  Mqondisi Tshabalala; Juanita Mellet; Kuben Vather; Derrick Nelson; Fathima Mohamed; Alan Christoffels; Michael S Pepper
Journal:  Front Genet       Date:  2022-03-04       Impact factor: 4.599

2.  Diversity of HLA Class I and Class II blocks and conserved extended haplotypes in Lacandon Mayans.

Authors:  Rodrigo Barquera; Joaquin Zuniga; José Flores-Rivera; Teresa Corona; Bridget S Penman; Diana Iraíz Hernández-Zaragoza; Manuel Soler; Letisia Jonapá-Gómez; Kalyan C Mallempati; Petra Yescas; Adriana Ochoa-Morales; Konstantinos Barsakis; José Artemio Aguilar-Vázquez; Maricela García-Lechuga; Michael Mindrinos; María Yunis; Luis Jiménez-Alvarez; Lourdes Mena-Hernández; Esteban Ortega; Alfredo Cruz-Lagunas; Víctor Hugo Tovar-Méndez; Julio Granados; Marcelo Fernández-Viña; Edmond Yunis
Journal:  Sci Rep       Date:  2020-02-24       Impact factor: 4.379
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.