Literature DB >> 2831503

The genetic structure of mouse ornithine transcarbamylase.

S E Scherer1, G Veres, C T Caskey.   

Abstract

The gene encoding the mouse urea cycle enzyme, ornithine transcarbamylase has been isolated on five partially overlapping bacteriophage lambda clones. We have characterized the gene and found that it is split between ten exons distributed over approximately 70 kb of the X chromosome. The introns range in size from 88 bases to the relatively unusual size of approximately 26 kilobases, while the splice donor/splice acceptor sequences conform to the consensus established for other eukaryotic genes.

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Year:  1988        PMID： 2831503      PMCID： PMC336337          DOI： 10.1093/nar/16.4.1593

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  25 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Screening lambdagt recombinant clones by hybridization to single plaques in situ.

Authors:  W D Benton; R W Davis
Journal:  Science       Date:  1977-04-08       Impact factor: 47.728

3.  The bidirectional transfer of DNA and RNA to nitrocellulose or diazobenzyloxymethyl-paper.

Authors:  G E Smith; M D Summers
Journal:  Anal Biochem       Date:  1980-11-15       Impact factor: 3.365

4.  New M13 vectors for cloning.

Authors:  J Messing
Journal:  Methods Enzymol       Date:  1983       Impact factor: 1.600

Review 5.  Organization and expression of eucaryotic split genes coding for proteins.

Authors:  R Breathnach; P Chambon
Journal:  Annu Rev Biochem       Date:  1981       Impact factor: 23.643

6.  Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

Authors:  M D Biggin; T J Gibson; G F Hong
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

7.  Structure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase.

Authors:  A L Horwich; W A Fenton; K R Williams; F Kalousek; J P Kraus; R F Doolittle; W Konigsberg; L E Rosenberg
Journal:  Science       Date:  1984-06-08       Impact factor: 47.728

8.  Citrulline synthesis in rat tissues and liver content of carbamoyl phosphate and ornithine.

Authors:  L Raijman
Journal:  Biochem J       Date:  1974-02       Impact factor: 3.857

9.  In vitro synthesis of a putative precursor of mitochondrial ornithine transcarbamoylase.

Authors:  J G Conboy; F Kalousek; L E Rosenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1979-11       Impact factor: 11.205

Review 10.  Ornithine transcarbamylase in liver mitochondria.

Authors:  M Mori; S Miura; T Morita; M Takiguchi; M Tatibana
Journal:  Mol Cell Biochem       Date:  1982-11-26       Impact factor: 3.396
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  10 in total

1.  Simultaneous detection of mutant gene and transgene in ornithine carbamoyl-transferase-deficient spf-ash mice with rat OCT gene.

Authors:  K Kobayashi; M Horiuchi; A Yokokouji; T Shimada; T Saheki
Journal:  J Inherit Metab Dis       Date:  1992       Impact factor: 4.982

2.  Origin, structure, and regulation of argK, encoding the phaseolotoxin-resistant ornithine carbamoyltransferase in Pseudomonas syringae pv. phaseolicola, and functional expression of argK in transgenic tobacco.

Authors:  E Hatziloukas; N J Panopoulos
Journal:  J Bacteriol       Date:  1992-09       Impact factor: 3.490

3.  Corruption of genomic databases with anomalous sequence.

Authors:  E D Lamperti; J M Kittelberger; T F Smith; L Villa-Komaroff
Journal:  Nucleic Acids Res       Date:  1992-06-11       Impact factor: 16.971

4.  Directed mutagenesis of YAC-cloned DNA using a rapid, PCR-based screening protocol.

Authors:  R M Tucker; D T Burke
Journal:  Nucleic Acids Res       Date:  1996-09-01       Impact factor: 16.971

5.  Chromosome localization of the genes for growth hormone, somatostatin peptide, ornithine transcarbamylase, and prion protein in silver fox (Vulpes fulvus).

Authors:  I V Koroleva; S N Malchenko; K Brusgaard; T M Khlebodarova; N Rubtsov; S M Zakian
Journal:  Mamm Genome       Date:  1996-11       Impact factor: 2.957

Review 6.  Transcriptional regulation of genes for ornithine cycle enzymes.

Authors:  M Takiguchi; M Mori
Journal:  Biochem J       Date:  1995-12-15       Impact factor: 3.857

7.  The spfash mouse: a missense mutation in the ornithine transcarbamylase gene also causes aberrant mRNA splicing.

Authors:  P E Hodges; L E Rosenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1989-06       Impact factor: 11.205

8.  Scanning detection of mutations in human ornithine transcarbamoylase by chemical mismatch cleavage.

Authors:  M Grompe; D M Muzny; C T Caskey
Journal:  Proc Natl Acad Sci U S A       Date:  1989-08       Impact factor: 11.205

9.  Human liver-type arginase gene: structure of the gene and analysis of the promoter region.

Authors:  M Takiguchi; Y Haraguchi; M Mori
Journal:  Nucleic Acids Res       Date:  1988-09-26       Impact factor: 16.971

10.  Promoter and 11-kilobase upstream enhancer elements responsible for hepatoma cell-specific expression of the rat ornithine transcarbamylase gene.

Authors:  T Murakami; A Nishiyori; M Takiguchi; M Mori
Journal:  Mol Cell Biol       Date:  1990-03       Impact factor: 4.272
  10 in total

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