Literature DB >> 28314253

The role of IL-7 in Immunity and Cancer.

Jack Lin1, Ziwen Zhu2, Huaping Xiao1,3, Mark R Wakefield2, Vivi A Ding1, Qian Bai2, Yujiang Fang4,2.   

Abstract

Interleukin-7 (IL-7) is a cytokine that has been known since long in immunology, mainly regarding its effects on T-cells and B-cells. IL-7 has been demonstrated to be necessary for both B-cell and T-cell proliferation and lack of IL-7 causes immature immune cell arrest. Interestingly, in recent years, certain studies have strongly suggested that the role of IL-7 is far beyond the field of immunology, it might have direct or indirect effect on cancer. This review aims to summarize the role of IL-7 in immunity and its role in the pathogenesis of neoplasia. Copyright
© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  IL-7; immunity cancer; review

Mesh:

Substances:

Year:  2017        PMID: 28314253     DOI: 10.21873/anticanres.11405

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  34 in total

1.  Rodent vertical sleeve gastrectomy alters maternal immune health and fetoplacental development.

Authors:  Redin A Spann; William J Lawson; Gene L Bidwell; C Austin Zamarripa; Rodrigo O Maranon; Sibali Bandyopadhyay; Erin R Taylor; Jane F Reckelhoff; Michael R Garrett; Bernadette E Grayson
Journal:  Clin Sci (Lond)       Date:  2018-01-25       Impact factor: 6.124

Review 2.  IL-2 and Beyond in Cancer Immunotherapy.

Authors:  John M Wrangle; Alicia Patterson; C Bryce Johnson; Daniel J Neitzke; Shikhar Mehrotra; Chadrick E Denlinger; Chrystal M Paulos; Zihai Li; David J Cole; Mark P Rubinstein
Journal:  J Interferon Cytokine Res       Date:  2018-02       Impact factor: 2.607

Review 3.  The role of interleukins and the widely studied TNF-α in non-Hodgkin's lymphoma.

Authors:  Kyle P D'mello; Lei Zhao; Erin C Kaser; Ziwen Zhu; Huaping Xiao; Mark R Wakefield; Qian Bai; Yujiang Fang
Journal:  Med Oncol       Date:  2021-04-09       Impact factor: 3.064

4.  Clinical outcomes of atezolizumab in combination with etoposide/platinum for treatment of extensive-stage small-cell lung cancer: A real-world, multicenter, retrospective, controlled study in China.

Authors:  Hanxiao Chen; Xiangjuan Ma; Jie Liu; Yu Yang; Yong Fang; Liping Wang; Jian Fang; Jun Zhao; Minglei Zhuo
Journal:  Chin J Cancer Res       Date:  2022-08-30       Impact factor: 4.026

5.  Interleukin-7 regulates CD127 expression and promotes CD8+ T cell activity in patients with primary cutaneous melanoma.

Authors:  Hongxia He; Binjun Qiao; Shuping Guo; Hongzhou Cui; Ziyan Zhang; Junxia Qin
Journal:  BMC Immunol       Date:  2022-07-18       Impact factor: 3.594

Review 6.  The generation and application of antigen-specific T cell therapies for cancer and viral-associated disease.

Authors:  Amy B Hont; Allison B Powell; Danielle K Sohai; Izabella K Valdez; Maja Stanojevic; Ashley E Geiger; Kajal Chaudhary; Ehsan Dowlati; Catherine M Bollard; Conrad Russell Y Cruz
Journal:  Mol Ther       Date:  2022-02-09       Impact factor: 12.910

Review 7.  The Role of Targeted Agents and Immunotherapy in Older Patients with Non-small Cell Lung Cancer.

Authors:  Fabio Gomes; Rebecca Tay; Jaseela Chiramel; Raffaele Califano
Journal:  Drugs Aging       Date:  2018-09       Impact factor: 3.923

8.  Interleukin (IL)-7 Signaling in the Tumor Microenvironment.

Authors:  Iwona Bednarz-Misa; Mariusz A Bromke; Małgorzata Krzystek-Korpacka
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

Review 9.  Interleukins in cancer: from biology to therapy.

Authors:  Daria Briukhovetska; Janina Dörr; Stefan Endres; Peter Libby; Charles A Dinarello; Sebastian Kobold
Journal:  Nat Rev Cancer       Date:  2021-06-03       Impact factor: 69.800

10.  Exercise training partially rescues impaired mucosal associated invariant t-cell mobilization in breast cancer survivors compared to healthy older women.

Authors:  Erik D Hanson; Lauren C Bates; Elizabeth P Harrell; David B Bartlett; Jordan T Lee; Chad W Wagoner; Mohamdod S Alzer; Dean J Amatuli; Brian C Jensen; Allison M Deal; Hyman B Muss; Kirsten A Nyrop; Claudio L Battaglini
Journal:  Exp Gerontol       Date:  2021-06-16       Impact factor: 4.253

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