Literature DB >> 28314197

Use of hepatobiliary phase images in Gd-EOB-DTPA-enhanced MRI of breast cancer hepatic metastasis to predict response to chemotherapy.

Hyun Ji Lee1, Chang Hee Lee2, Jeong Woo Kim1, Yang Shin Park1, Jongmee Lee1, Kyeong Ah Kim1.   

Abstract

OBJECTIVES: To determine the prognostic value of Gd-EOB-DTPA MRI findings of liver metastasis from breast cancer.
METHODS: 29 metastatic lesions from 12 breast cancer patients who received chemotherapy were retrospectively reviewed. We evaluated hepatobiliary phase of the lesions and classified them as a "target" or "non-target" appearance. The relationship of appearance or SI ratio with tumor response was analyzed.
RESULTS: A non-target appearance was more frequent in disease control group than in non-control group [14/18 (77.8%) vs. 4/18 (22.2%)], and it was associated with a better response [p=0.048].
CONCLUSION: HBP analysis may be useful to predict the response to chemotherapy and survival.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Breast cancer liver metastases; Chemotherapy response; Gadoxetic acid; Hepatobiliary phase (HBP); MRI

Mesh:

Substances:

Year:  2017        PMID: 28314197     DOI: 10.1016/j.clinimag.2017.03.005

Source DB:  PubMed          Journal:  Clin Imaging        ISSN: 0899-7071            Impact factor:   1.605


  2 in total

Review 1.  Cytoreduction for colorectal metastases: liver, lung, peritoneum, lymph nodes, bone, brain. When does it palliate, prolong survival, and potentially cure?

Authors:  Camille L Stewart; Susanne Warner; Kaori Ito; Mustafa Raoof; Geena X Wu; Jonathan Kessler; Jae Y Kim; Yuman Fong
Journal:  Curr Probl Surg       Date:  2018-10-04       Impact factor: 1.909

2.  Long Non-Coding RNA (LncRNA) HOXA11-AS Promotes Breast Cancer Invasion and Metastasis by Regulating Epithelial-Mesenchymal Transition.

Authors:  Wenlei Li; Guotao Jia; Yanwen Qu; Qian Du; Baoguo Liu; Bin Liu
Journal:  Med Sci Monit       Date:  2017-07-13
  2 in total

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