| Literature DB >> 28306508 |
Abstract
In this issue, Swarts et al. (2017) discover that prokaryotic Argonaute proteins generate their own DNA guide strands through a newly characterized, unguided "chopping" activity. Double-stranded chopping products are selectively loaded onto Argonaute, enabling DNA-guided defense against foreign DNA.Mesh:
Substances:
Year: 2017 PMID: 28306508 DOI: 10.1016/j.molcel.2017.03.002
Source DB: PubMed Journal: Mol Cell ISSN: 1097-2765 Impact factor: 17.970