Literature DB >> 28306350

The utility of target-based discovery.

Glenn E Croston1.   

Abstract

Mesh:

Year:  2017        PMID: 28306350     DOI: 10.1080/17460441.2017.1308351

Source DB:  PubMed          Journal:  Expert Opin Drug Discov        ISSN: 1746-0441            Impact factor:   6.098


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  18 in total

1.  The Resurrection of Phenotypic Drug Discovery.

Authors:  Wayne E Childers; Khaled M Elokely; Magid Abou-Gharbia
Journal:  ACS Med Chem Lett       Date:  2020-03-06       Impact factor: 4.345

2.  Increased Molecular Flexibility Widens the Gap between K i and K d values in Screening for Retinoid X Receptor Modulators.

Authors:  Masaki Watanabe; Mariko Nakamura-Nakayama; Michiko Fujihara; Mayu Kawasaki; Shogo Nakano; Hiroki Kakuta
Journal:  ACS Med Chem Lett       Date:  2022-01-21       Impact factor: 4.345

3.  Quantitative Proteomics Reveals Cellular Off-Targets of a DDR1 Inhibitor.

Authors:  Jiaqian Xu; Zhang Zhang; Ligen Lin; Hongyan Sun; Lorenzo V White; Ke Ding; Zhengqiu Li
Journal:  ACS Med Chem Lett       Date:  2020-02-05       Impact factor: 4.345

Review 4.  Phenotypic Screening in C. elegans as a Tool for the Discovery of New Geroprotective Drugs.

Authors:  Sven Bulterijs; Bart P Braeckman
Journal:  Pharmaceuticals (Basel)       Date:  2020-07-25

Review 5.  Emerging drug development technologies targeting ubiquitination for cancer therapeutics.

Authors:  Gianluca Veggiani; María Carla Rosales Gerpe; Sachdev S Sidhu; Wei Zhang
Journal:  Pharmacol Ther       Date:  2019-03-07       Impact factor: 12.310

6.  An in silico Approach for Integrating Phenotypic and Target-based Approaches in Drug Discovery.

Authors:  Hiroaki Iwata; Ryosuke Kojima; Yasushi Okuno
Journal:  Mol Inform       Date:  2019-10-22       Impact factor: 3.353

Review 7.  Schistosomiasis Drug Discovery in the Era of Automation and Artificial Intelligence.

Authors:  José T Moreira-Filho; Arthur C Silva; Rafael F Dantas; Barbara F Gomes; Lauro R Souza Neto; Jose Brandao-Neto; Raymond J Owens; Nicholas Furnham; Bruno J Neves; Floriano P Silva-Junior; Carolina H Andrade
Journal:  Front Immunol       Date:  2021-05-31       Impact factor: 7.561

Review 8.  Revisiting potential druggable targets against SARS-CoV-2 and repurposing therapeutics under preclinical study and clinical trials: A comprehensive review.

Authors:  Abdullah Al Mamun Sohag; Md Abdul Hannan; Sadaqur Rahman; Motaher Hossain; Mahmudul Hasan; Md Kawsar Khan; Amena Khatun; Raju Dash; Md Jamal Uddin
Journal:  Drug Dev Res       Date:  2020-07-06       Impact factor: 5.004

9.  A Phenotarget Approach for Identifying an Alkaloid Interacting with the Tuberculosis Protein Rv1466.

Authors:  Yan Xie; Yunjiang Feng; Angela Di Capua; Tin Mak; Garry W Buchko; Peter J Myler; Miaomiao Liu; Ronald J Quinn
Journal:  Mar Drugs       Date:  2020-03-05       Impact factor: 5.118

Review 10.  Evolving a Peptide: Library Platforms and Diversification Strategies.

Authors:  Krištof Bozovičar; Tomaž Bratkovič
Journal:  Int J Mol Sci       Date:  2019-12-27       Impact factor: 5.923

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