Literature DB >> 28306005

The function ofbithorax genes in the abdominal central nervous system ofDrosophila.

Alain Ghysen1, Edward B Lewis2.   

Abstract

We have analysed the influence of the bithorax gene complex (BX-C) on two segment-specific features of the central nervous system ofDrosophila larvae: the "presumptive leg neuromeres" (PLN), which are present only in the thoracic ganglia of the larva and develop into the leg neuromeres of the adult fly during metamorphosis; and the "lateral dots" (LD) which are found in the first abdominal as well as thoracic ganglia. We show in both cases that consecutive BX-C genes can suppress the development of these structures. We also show that each gene is expressed in several consecutive segments, leading to an apparent redundancy of the suppression in posterior segments.

Entities:  

Keywords:  Bithorax complex; Drosophila CNS; Segmental determination

Year:  1986        PMID: 28306005     DOI: 10.1007/BF02438952

Source DB:  PubMed          Journal:  Rouxs Arch Dev Biol        ISSN: 0930-035X


  12 in total

1.  A gene complex controlling segmentation in Drosophila.

Authors:  E B Lewis
Journal:  Nature       Date:  1978-12-07       Impact factor: 49.962

2.  Molecular Genetics of the Bithorax Complex in Drosophila melanogaster.

Authors:  W Bender; M Akam; F Karch; P A Beachy; M Peifer; P Spierer; E B Lewis; D S Hogness
Journal:  Science       Date:  1983-07-01       Impact factor: 47.728

3.  Pseudoallelism and gene evolution.

Authors:  E B LEWIS
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1951

4.  A cell arrangement specific to thoracic ganglia in the central nervous system of theDrosophila embryo: Its behaviour in homoeotic mutants.

Authors:  F Jiménez; J A Campos-Ortega
Journal:  Wilehm Roux Arch Dev Biol       Date:  1981-11

5.  The abdominal region of the bithorax complex.

Authors:  F Karch; B Weiffenbach; M Peifer; W Bender; I Duncan; S Celniker; M Crosby; E B Lewis
Journal:  Cell       Date:  1985-11       Impact factor: 41.582

6.  Duplicated neural structure in bithorax mutant Drosophila.

Authors:  J B Thomas; R J Wyman
Journal:  Dev Biol       Date:  1984-04       Impact factor: 3.582

7.  Developmental effects of some newly induced Ultrabithorax alleles of Drosophila.

Authors:  S Kerridge; G Morata
Journal:  J Embryol Exp Morphol       Date:  1982-04

8.  The genetic specification of pattern in a Drosophila muscle.

Authors:  P A Lawrence; P Johnston
Journal:  Cell       Date:  1984-03       Impact factor: 41.582

9.  A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes.

Authors:  W McGinnis; M S Levine; E Hafen; A Kuroiwa; W J Gehring
Journal:  Nature       Date:  1984 Mar 29-Apr 4       Impact factor: 49.962

10.  The location of Ultrabithorax transcripts in Drosophila tissue sections.

Authors:  M E Akam
Journal:  EMBO J       Date:  1983       Impact factor: 11.598

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  1 in total

1.  Mutational dissection of gene expression in the abdominal region of the bithorax complex of Drosophila in imaginal tissue.

Authors:  Stanley Y K Tiong; Mary Clare Gribbin; James Robert Stuart Whittle
Journal:  Rouxs Arch Dev Biol       Date:  1988-05
  1 in total

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