| Literature DB >> 28305373 |
H Oberlander1, C E Leach1, D E Lynn2.
Abstract
A clone (GV1) of the CHIManduca sexta cell line responds to 20-hydroxy-ecdysone by changing cellular shape from an epithelial-like form to an elongated fibroblast-like form. We have determined that this morphological response to hormone is prevented by treatment with cycloheximide. The inhibition of the elongation response by cycloheximide may relate to a requirement for the synthesis of specific proteins that play a role in the formation of cytoskeletal structure.Entities:
Keywords: 20-hydroxy-ecdysone, insect tissue culture; Cycloheximide; Manduca sexta
Year: 1981 PMID: 28305373 DOI: 10.1007/BF00868706
Source DB: PubMed Journal: Wilehm Roux Arch Dev Biol ISSN: 0340-0794