Literature DB >> 28304714

The effects of bromodeoxyuridine and bromouracil on regeneration inHydra.

M H Goyns1, M Stanisstreet1.   

Abstract

The effects on tentacle regeneration inHydra of two DNA-antimetabolites, bromouracil and bromodeoxyuridine, have been studied. Bromouracil inhibits tentacle regeneration inH. vulgaris andH. viridis; bromodeoxynridine inhibits tentacle regeneration inH. vulgaris but notH. viridis over the range of concentrations studied. Thus these two species appear to differ in their susceptibilities to these drugs, and the drugs may have different efficacies in this system.

Entities:  

Year:  1974        PMID： 28304714     DOI： 10.1007/BF00574294

Source DB:  PubMed          Journal:  Wilhelm Roux Arch Entwickl Mech Org        ISSN： 0043-5546


  7 in total

1.  Hydra: induction of supernumerary heads by isolated neurosecretory granules.

Authors:  T L Lentz
Journal:  Science       Date:  1965-10-29       Impact factor: 47.728

2.  The role of mesoglea in mass cell movement in Hydra.

Authors:  S Shostak; N G Patel; A L Burnett
Journal:  Dev Biol       Date:  1965-12       Impact factor: 3.582

3.  Differentiation in the presence of bromodeoxyuridine id "all-or-none".

Authors:  H Weintraub; G L Campbell; H Holtzer
Journal:  Nat New Biol       Date:  1973-08-01

4.  Isolation and characterization of a low-molecular-weight substance activating head and bud formation in hydra.

Authors:  H C Schaller
Journal:  J Embryol Exp Morphol       Date:  1973-02

Review 5.  Positional information and pattern formation.

Authors:  L Wolpert
Journal:  Curr Top Dev Biol       Date:  1971       Impact factor: 4.897

6.  A clonal study of the reversible inhibition of muscle differentiation by the halogenated thymidine analog 5-bromodeoxyuridine.

Authors:  J R Coleman; A W Coleman; E J Hartline
Journal:  Dev Biol       Date:  1969-06       Impact factor: 3.582

7.  The effects of 5-Bromodeoxyuridine on the differentiation of chondrocytes in vitro.

Authors:  R Lasher; R D Cahn
Journal:  Dev Biol       Date:  1969-05       Impact factor: 3.582
  7 in total
  1 in total

1.  The influence of BrdU on interstitial cell differentiation in hydra.

Authors:  G E Lesh-Laurie; W N Frank
Journal:  Experientia       Date:  1977-07-15
  1 in total

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