Karin Jepsen1, Martina Stefanini2, Mariano Sanz3, Giovanni Zucchelli4, Søren Jepsen1. 1. Department of Periodontology, Operative and Preventive Dentistry, University of Bonn, Bonn, Germany. 2. Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy. 3. Department of Periodontology, University Complutense of Madrid, Madrid, Spain. 4. Department of Biomedical and Neuromotor Sciences, University of Bologna.
Abstract
BACKGROUND: This study compared 6-month and 3-year outcomes for root coverage (RC) by coronally advanced flap (CAF) procedures in localized gingival recessions. METHODS: Two centers, that had participated in a 6-month multinational multicenter randomized clinical trial (RCT), followed up 18 patients with 36 Miller Class I and II defects that had been treated in a split-mouth design with CAF procedures or CAF + xenogeneic collagen matrix (CMX). Percentage of RC, complete root coverage (CRC), width, and thickness of keratinized tissue were assessed by the same masked examiners as after the 6-month RCT. RESULTS: There was a high correlation between 6-month and 3-year RC outcomes for both CAF procedures. Mean RC after CAF + CMX amounted to 89.9% after 6 months and 91.7% after 3 years (Pearson's correlation: 0.91). Corresponding values for CAF were 83.7% versus 82.8% (Pearson's correlation: 0.94). Likewise, CRC was stable with 61%/61% for CAF + CMX and 39%/39% for CAF after 6 months/3 years, respectively. CONCLUSIONS: In this 3-year follow-up of a subgroup of patients from a previous 6-month RCT, there was a high correlation between the results for RC after 6 months and 3 years, indicating their stability. These data suggest that 6-month outcomes may be useful to predict long-term outcomes in CAF procedures with or without additional use of CMX.
RCT Entities:
BACKGROUND: This study compared 6-month and 3-year outcomes for root coverage (RC) by coronally advanced flap (CAF) procedures in localized gingival recessions. METHODS: Two centers, that had participated in a 6-month multinational multicenter randomized clinical trial (RCT), followed up 18 patients with 36 Miller Class I and II defects that had been treated in a split-mouth design with CAF procedures or CAF + xenogeneic collagen matrix (CMX). Percentage of RC, complete root coverage (CRC), width, and thickness of keratinized tissue were assessed by the same masked examiners as after the 6-month RCT. RESULTS: There was a high correlation between 6-month and 3-year RC outcomes for both CAF procedures. Mean RC after CAF + CMX amounted to 89.9% after 6 months and 91.7% after 3 years (Pearson's correlation: 0.91). Corresponding values for CAF were 83.7% versus 82.8% (Pearson's correlation: 0.94). Likewise, CRC was stable with 61%/61% for CAF + CMX and 39%/39% for CAF after 6 months/3 years, respectively. CONCLUSIONS: In this 3-year follow-up of a subgroup of patients from a previous 6-month RCT, there was a high correlation between the results for RC after 6 months and 3 years, indicating their stability. These data suggest that 6-month outcomes may be useful to predict long-term outcomes in CAF procedures with or without additional use of CMX.
Authors: Maurizio S Tonetti; Pierpaolo Cortellini; Gaia Pellegrini; Michele Nieri; Daniele Bonaccini; Mario Allegri; Philippe Bouchard; Francesco Cairo; Gianpaolo Conforti; Ioannis Fourmousis; Filippo Graziani; Adrian Guerrero; Jan Halben; Jacques Malet; Giulio Rasperini; Heinz Topoll; Hannes Wachtel; Beat Wallkamm; Ion Zabalegui; Otto Zuhr Journal: J Clin Periodontol Date: 2017-11-21 Impact factor: 8.728
Authors: A Stähli; H Y Duong; J C Imber; A Roccuzzo; G E Salvi; C Katsaros; C A Ramseier; A Sculean Journal: Clin Oral Investig Date: 2022-08-25 Impact factor: 3.606