Literature DB >> 28303792

Toward theoretical synthesis of biocomputer.

Ting-Yu Kuo1, Chun-Liang Lin2, Natdanai Charoenkit3, Yang-Yi Chen1, Chakkrit Preuksakarn3.   

Abstract

Increasing applications of fundamental biological gates have been successfully built during this decade. Proceeding to the current development, this study presents a genetic arithmetic and logical unit (ALU) design based on a series of genetic logic gates. The system level's architecture consists of three parts: temp register, ALU and accumulator register. Using the concept of the ALU on the digital computer, the authors present the fundamental function of the genetic ALU via full adder register and also build the bio-storage devices to store data generated from the genetic ALU. The system in this study shows the capability of computing and storage on the biocomputer.

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Year:  2017        PMID: 28303792      PMCID: PMC8687244          DOI: 10.1049/iet-syb.2016.0015

Source DB:  PubMed          Journal:  IET Syst Biol        ISSN: 1751-8849            Impact factor:   1.615


  24 in total

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Journal:  IEEE/ACM Trans Comput Biol Bioinform       Date:  2012 May-Jun       Impact factor: 3.710

Review 2.  Designing biological systems.

Authors:  David A Drubin; Jeffrey C Way; Pamela A Silver
Journal:  Genes Dev       Date:  2007-02-01       Impact factor: 11.361

3.  Genetic switchboard for synthetic biology applications.

Authors:  Jarred M Callura; Charles R Cantor; James J Collins
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-27       Impact factor: 11.205

4.  Genetic programs constructed from layered logic gates in single cells.

Authors:  Tae Seok Moon; Chunbo Lou; Alvin Tamsir; Brynne C Stanton; Christopher A Voigt
Journal:  Nature       Date:  2012-10-07       Impact factor: 49.962

5.  Higher-order cellular information processing with synthetic RNA devices.

Authors:  Maung Nyan Win; Christina D Smolke
Journal:  Science       Date:  2008-10-17       Impact factor: 47.728

6.  Construction of a genetic AND gate under a new standard for assembly of genetic parts.

Authors:  Shotaro Ayukawa; Akio Kobayashi; Yusaku Nakashima; Hidemasa Takagi; Shogo Hamada; Masahiko Uchiyama; Katsuyuki Yugi; Satoshi Murata; Yasubumi Sakakibara; Masami Hagiya; Masayuki Yamamura; Daisuke Kiga
Journal:  BMC Genomics       Date:  2010-12-02       Impact factor: 3.969

7.  Layering genetic circuits to build a single cell, bacterial half adder.

Authors:  Adison Wong; Huijuan Wang; Chueh Loo Poh; Richard I Kitney
Journal:  BMC Biol       Date:  2015-06-16       Impact factor: 7.431

8.  Design of synthetic genetic oscillators using evolutionary optimization.

Authors:  Yen-Chang Chang; Chun-Liang Lin; Tanagorn Jennawasin
Journal:  Evol Bioinform Online       Date:  2013-03-10       Impact factor: 1.625

9.  Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks.

Authors:  Marc R J Carlson; Bin Zhang; Zixing Fang; Paul S Mischel; Steve Horvath; Stanley F Nelson
Journal:  BMC Genomics       Date:  2006-03-03       Impact factor: 3.969

10.  Synthesizing genetic sequential logic circuit with clock pulse generator.

Authors:  Chia-Hua Chuang; Chun-Liang Lin
Journal:  BMC Syst Biol       Date:  2014-05-28
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  1 in total

1.  Synthesis of control unit for future biocomputer.

Authors:  Chun-Liang Lin; Ting-Yu Kuo; Wei-Xian Li
Journal:  J Biol Eng       Date:  2018-08-14       Impact factor: 4.355

  1 in total

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