Literature DB >> 28301358

Hyperbaric Oxygen Therapy: Exploring the Clinical Evidence.

Gretl Lam1, Rocky Fontaine, Frank L Ross, Ernest S Chiu.   

Abstract

GENERAL
PURPOSE: To provide information about hyperbaric oxygen therapy (HBOT), its mechanisms, indications and safe applications based on clinical evidence. TARGET AUDIENCE: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES: After participating in this educational activity, the participant should be better able to:1. Recall the physiology of wound healing and the mechanisms of action of HBOT.2. Identify current applications of HBOT based on clinical evidence as well as its risks and contraindications. ABSTRACT: Treating chronic wounds and infections are challenging medical problems worldwide. Hyperbaric oxygen therapy (HBOT), the administration of 100% oxygen at pressures greater than 1.4 atmosphere absolute in a series of treatments, can be used as an adjunctive therapy in many wound care settings because it improves oxygenation and neovascularization and decreases inflammation in chronic wounds. A growing number of studies support the benefits of HBOT for enhancing wound healing and decreasing the likelihood of negative events such as amputation. However, many practitioners are unfamiliar with HBOT. This article provides a general introduction to HBOT, reviews the physiology and mechanisms of behind HBOT, discusses all the indications for HBOT, and explores in-depth the clinical evidence for HBOT in the treatment of arterial insufficiencies, diabetic ulcers, delayed radiation injury, and chronic refractory osteomyelitis.

Entities:  

Mesh:

Year:  2017        PMID: 28301358     DOI: 10.1097/01.ASW.0000513089.75457.22

Source DB:  PubMed          Journal:  Adv Skin Wound Care        ISSN: 1527-7941            Impact factor:   2.347


  15 in total

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Authors:  Ralf Paus; Yuval Ramot; Robert S Kirsner; Marjana Tomic-Canic
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2.  Hyperbaric Oxygen Reduces Aspergillus fumigatus Proliferation In Vitro and Influences In Vivo Disease Outcomes.

Authors:  Sourabh Dhingra; Jay C Buckey; Robert A Cramer
Journal:  Antimicrob Agents Chemother       Date:  2018-02-23       Impact factor: 5.191

Review 3.  Breathing Aid Devices to Support Novel Coronavirus (COVID-19)Infected Patients.

Authors:  Md Milon Islam; Shah Muhammad Azmat Ullah; Saifuddin Mahmud; S M Taslim Uddin Raju
Journal:  SN Comput Sci       Date:  2020-08-19

4.  Markers of Pulmonary Oxygen Toxicity in Hyperbaric Oxygen Therapy Using Exhaled Breath Analysis.

Authors:  T T Wingelaar; P Brinkman; P J A M van Ooij; R Hoencamp; A H Maitland-van der Zee; M W Hollmann; R A van Hulst
Journal:  Front Physiol       Date:  2019-04-24       Impact factor: 4.566

5.  Effect of intermittent hyperoxia on stem cell mobilization and cytokine expression.

Authors:  Kent J MacLaughlin; Gregory P Barton; Rudolf K Braun; Marlowe W Eldridge
Journal:  Med Gas Res       Date:  2019 Jul-Sep

Review 6.  Clinical utility of hyperbaric oxygen therapy in dentistry.

Authors:  Kaitlyn Re; Shrey Patel; Jason Gandhi; Yiji Suh; Inefta Reid; Gunjan Joshi; Noel L Smith; Sardar Ali Khan
Journal:  Med Gas Res       Date:  2019 Apr-Jun

7.  Hyperbaric oxygen treatment for toxic epidermal necrolysis: A case report.

Authors:  Selin Gamze Sümen; Sezer Yakupoğlu; Tuna Gümüş; Nur Benzonana
Journal:  Diving Hyperb Med       Date:  2021-06-30       Impact factor: 1.228

Review 8.  Recent Advances in Non-Conventional Antimicrobial Approaches for Chronic Wound Biofilms: Have We Found the 'Chink in the Armor'?

Authors:  Snehal Kadam; Saptarsi Shai; Aditi Shahane; Karishma S Kaushik
Journal:  Biomedicines       Date:  2019-04-30

9.  Randomized controlled clinical trial evaluating the efficacy of hyperbaric oxygen therapy in facilitating the healing of chronic foot ulcers in diabetic patients: the study protocol.

Authors:  Jocefábia Reika Alves Lopes; Mariza D'Agostino Dias; João Antonio Correa; Maria Alice Bragagnolo Batalha; Luanda Karla Dantas Guerra
Journal:  Trials       Date:  2020-09-29       Impact factor: 2.279

10.  Hyperbaric Oxygen Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.

Authors:  Yuan Yuan; Yali Li; Guoqiang Qiao; Yilu Zhou; Zijian Xu; Charlotte Hill; Zhenglin Jiang; Yihua Wang
Journal:  Front Mol Biosci       Date:  2021-06-04
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