Literature DB >> 28300935

Specific and social fears in children and adolescents: separating normative fears from problem indicators and phobias.

Paola P Laporte1,2, Pedro M Pan1,3, Mauricio S Hoffmann1,2, Lauren S Wakschlag4, Luis A Rohde1,2,5, Euripedes C Miguel1,2,5, Daniel S Pine6, Gisele G Manfro1,2, Giovanni A Salum1,2.   

Abstract

OBJECTIVE: : To distinguish normative fears from problematic fears and phobias.
METHODS: : We investigated 2,512 children and adolescents from a large community school-based study, the High Risk Study for Psychiatric Disorders. Parent reports of 18 fears and psychiatric diagnosis were investigated. We used two analytical approaches: confirmatory factor analysis (CFA)/item response theory (IRT) and nonparametric receiver operating characteristic (ROC) curve.
RESULTS: : According to IRT and ROC analyses, social fears are more likely to indicate problems and phobias than specific fears. Most specific fears were normative when mild; all specific fears indicate problems when pervasive. In addition, the situational fear of toilets and people who look unusual were highly indicative of specific phobia. Among social fears, those not restricted to performance and fear of writing in front of others indicate problems when mild. All social fears indicate problems and are highly indicative of social phobia when pervasive.
CONCLUSION: : These preliminary findings provide guidance for clinicians and researchers to determine the boundaries that separate normative fears from problem indicators in children and adolescents, and indicate a differential severity threshold for specific and social fears.

Entities:  

Mesh:

Year:  2017        PMID: 28300935      PMCID: PMC7111439          DOI: 10.1590/1516-4446-2016-2064

Source DB:  PubMed          Journal:  Braz J Psychiatry        ISSN: 1516-4446            Impact factor:   2.697


Introduction

Fear is broadly defined as a negative emotional state triggered by the presence of a stimulus that has the potential to cause harm. It is an adaptive emotion and essential for survival. However, when intensity, duration, and/or frequency are disproportionate to the eliciting threat, and thereby cause interference or excessive distress, such fears may indicate the presence of a mental disorder requiring treatment.1 Mental disorders are described as a list of heterogeneous symptoms not organized according to variations in their severity. However, although children can fear a variety of things and situations, more data are needed to identify which fears are most likely to indicate the presence of a significant clinical problem and the presence of specific and social phobia diagnoses.2 The normative fears observed in most children and adolescents are typically transient. Specific and social fears, considering both their mild and severe forms, touch almost all children and adolescents.3,4 In contrast, clinically significant specific phobias and social phobias are characterized by one or more persistent fears that cause distress and impairment to the child’s life.1,5 The prevalence of specific and social phobia in children and adolescents is 2.9 and 0.3% respectively.6 In short, the presence of fears is typically normative, and only a minority of children is significantly impaired by fears requiring clinical attention. Previous studies that evaluated youth in community samples investigated whether a specific fear indicated a disorder according to the number of feared objects/situations. This research showed that the number of fears was positively associated with a higher probability of meeting diagnostic criteria for specific phobia,3 another anxiety disorder, or having another psychiatric comorbidity.3,7 With respect to social fears, studies that evaluated adolescents in community samples also investigated the role of the number of feared social situations. These investigations found that the number of social fears was significantly associated with higher comorbidity rates, functional impairment, and prevalence of lifetime treatment.8 In addition, adolescents with generalized social phobia (i.e., those who fear most social situations) had earlier age of onset9 and experienced a higher degree of clinical severity as compared to adolescents with non-generalized social phobia.10 To date, the literature has been limited to investigating how the number of feared situations and objects might provide insight into clinically relevant situations. However, indicators that differentiate normative from clinical fears are unknown. Among existing methods to discriminate the severity of different types of symptoms, two have received particularly little attention in the fear literature: confirmatory factor analysis (CFA)/item response theory (IRT) and signal detection theory (SDT). CFA with binary outcomes and two-parameter normal-ogive IRT are equivalent to each other.11 The underlying assumption of these methods is that items (i.e., symptoms) are endorsed (i.e., reported) by subjects as a function of their severity on a specific latent trait (i.e., how much fear they experience). These techniques allow scaling items and people on the same underlying dimensional continuum.12 Individual items are assigned to a severity score, and an individual score on the dimension can be used as an estimate of the overall severity of fears.13 In contrast, SDT aims to quantify the ability to discriminate between stimuli and random patterns that distract from true information.14 SDT has wide applications in biomedical sciences, including use of the receiver operating characteristic (ROC) curve.15 The ROC curve represents the relationship between sensitivity and specificity by plotting the true-positive rate (in this case, phobia diagnosis) against the false-positive rate at various threshold settings to detect a significant medical problem.16 The existing literature is limited in many significant ways. First, no previous study has used modern psychometric analysis and SDT to assess the thresholds separating normative fear from problem indicators. Second, most of the current literature focuses on older adolescent and adult populations,10,16-22 with few studies including children and early adolescents.23 Finally, the majority of studies are limited to small samples sizes or selected by clinical condition, which limits the ability to use IRT and SDT, respectively. Here, we address these issues by using CFA/IRT for problem prediction and ROC analysis for diagnostic prediction in a large, non-referred community sample of children aged 6-14. These techniques were applied to elucidate which of a list of 18 fears are more likely to be normative fear expressions and which are more likely to represent a clinically significant problem.

Methods

Sample description

The sample was obtained from a large community school-based study, the High Risk Study for Psychiatric Disorders.6 Further details are available elsewhere.6 Briefly, after a screening phase, 2,512 subjects were selected for further assessment by a simple randomization procedure that selects a high risk sample (n=1,554), using a risk prioritization procedure that consists of selecting individuals with high family loading of symptoms and ongoing psychiatric symptoms, as well as a random-selection subgroup (n=958). The study was previously approved by the Ethics Committee at Universidade de São Paulo, and written informed consent was obtained from the parents of all participants.

Instruments

Specific and social fears assessment

Specific and social fears were investigated using 18 questions from the specific and social phobia sections of the Development and Well-Being Assessment (DAWBA)24 posed to a parental informant. The specific phobia session consists of 12 questions about specific fears, while the social phobia section comprises six questions about social fears. All questions have three response categories: no, a little, and a lot. In the social phobia section, we removed the skipping rule for the first question (Does child particularly fear or avoid social situations?), in order to have the six social fears included for all participants.

Diagnostic assessment

Psychiatric diagnosis was investigated using the Brazilian Portuguese version of the DAWBA,25 answered by the child’s main caregiver. The DAWBA was administered by lay interviewers, and both structured answers and verbatim responses of any reported problems recorded. Psychiatrists confirmed, refuted, or altered initial computerized diagnosis after evaluating the structured answers and verbatim responses. All questions are based on the DSM-IV diagnostic criteria, which, for diagnoses of social and specific phobia, include: a) marked and persistent fear that is excessive or unreasonable; b) the phobic stimulus almost invariably provokes an immediate anxiety response; c) fear is excessive or unreasonable; d) the phobic situation is avoided or endured with intense anxiety or distress; e) avoidance, anxious anticipation, or distress in the feared situation interferes with the person’s life; f) in individuals under age 18 years, the duration is at least 6 months; and g) fears are not better accounted for by another mental disorder.26 The DAWBA is reliable and well suited for epidemiological research. The Brazilian Portuguese version shows appropriate psychometric proprieties and high inter-rater reliability,6 as well as good reliability for diagnosis of emotional disorders (kappa = 0.84).6

Statistical analysis

Confirmatory factor analysis

The 18 fear items were included in a CFA analysis using one-dimensional (all items loading into a single factor), correlated (six social items loading into a social latent factor; 12 specific items loading into a specific latent factor), and bifactor models (all items loading into a general factor and residuals not explained by the general factor loading into two group factors - specific and social). For all CFA models, we used delta parameterization and weighted least-square parameters using a diagonal weight matrix with standard errors and with mean and variance-adjusted chi-square test statistics (WLSMV) estimators. Goodness of fit was assessed using four indices: the chi-square test of model fit, Tucker-Lewis index (TLI), comparative fit index (CFI), and root mean square error of approximation (RMSEA). TLI and CFI values > 0.95 and RMSEA values < 0.06 represent good-to-excellent model fit.1 The comparison between these three nested models was tested for differences using a chi-square test run with the DIFFTEST command in MPLUS 7.3 software.27

Defining a problem indicator (CFA and IRT)

CFA estimates from the best-fitting model previously tested were used to estimate factor loadings (λ) and item category thresholds (τ). In addition, we also performed unidimensional IRT analysis using the graded response model28 to estimate GRM item parameters reflecting the item discrimination or slope (a) and item difficulty (b) for each item. Factor loadings from CFA are analogous to item discrimination parameters from IRT, and represent the strength of the relationship between latent trait and item responses, or how well the item discriminates different severity levels. Category thresholds from CFA are analogous to item difficulty parameters from IRT insofar as they are used to indicate the expected value of the latent factor at which there is a 50% probability of endorsing a given category of higher. The category thresholds roughly indicate the severity level at which the transition from one response category to the next is likely to happen (e.g., from no to a little or higher, from a little to a lot). Higher thresholds indicate that, to be severe, a given item must be endorsed at a given response category or higher. In this sample, as suggested by Wakschlag et al.,29 latent trait values at or above the 95th percentile of the sample distribution were chosen to define a problem indicator, which represents a b of 1.53 in the IRT metric and a category threshold of 0.78 in the CFA metric for the bifactor model (general factor). A problem indicator was defined as those items meeting problem indicator criteria in both CFA and IRT analysis.

Defining a diagnostic indicator (SDT)

Nonparametric ROC curves were used to analyze associations between specific and social fears with specific and social phobia diagnosis. The following indexes were estimated: area under the curve (AUC; probability of identifying cases), sensitivity (Sn; the percentage of true cases correctly classified), specificity (Sp; the percentage of true non-cases correctly classified), positive likelihood ratio (LR+; [Sn/{1-Sp}].), and negative likelihood ratio (LR-; [{1-Sn}/Sp].). Likelihood ratios assess the relative proportions of screened positives versus confirmed cases (LR+) or non-cases (LR-). LR+ values ≥ 5 and LR- values ≤ 0.2 are considered useful, whereas LR+ values ≥ 10 and LR- values ≤ 0.1 are considered sufficient to rule in or out the diagnosis.16,30

Results

Prevalence

Our data suggest that fears occur normatively and are extremely prevalent in children and adolescents. Among the randomly selected subjects, 86.5% (n=829) presented at least one mild specific fear and 32.1% (n=308) presented at least one mild social fear. Specific fears were more common than social fears (the mean prevalence of specific fears graded as a little or higher was 26%, while the mean prevalence of social fears graded as such was 11.7%) (Table 1). Prevalence rates by age and group are available from the corresponding author.
Table 1

Prevalence of common fears in the randomly selected sample (n=958)

Fear listNoA littleA lot
Specific fears
    Animals443 (46.2)382 (39.9)133 (13.9)
    Natural environments
        Storms, thunder, heights550 (57.4)295 (30.8)113 (11.8)
        Dark503 (52.5)315 (32.9)140 (14.6)
    Blood, injection, injury
        Blood, injection, injury525 (54.8)308 (32.2)125 (13.0)
        Dentists, doctors712 (74.3)186 (19.4)60 (6.3)
    Situational
        Modes of transport894 (93.3)49 (5.1)15 (1.6)
        Enclosed spaces861 (89.9)73 (7.6)24 (2.5)
        Toilets882 (92.1)60 (6.3)16 (1.7)
    Others
        Monsters700 (73.1)197 (20.6)61 (6.4)
        Vomiting, choking, diseases774 (80.8)145 (15.1)39 (4.1)
        Loud noises800 (83.5)120 (12.5)38 (4.0)
        People who look unusual874 (91.2)67 (7.0)17 (1.8)
Social fears
    Not restricted to performance
        Meeting new people913 (95.3)39 (4.1)6 (0.6)
        Meeting a lot of people902 (94.2)44 (4.6)12 (1.3)
        Eating in front of others900 (93.9)49 (5.1)9 (0.9)
    Performance-related only
        Speaking in class794 (82.9)141 (14.7)23 (2.4)
        Reading aloud in front of others730 (76.2)181 (18.9)47 (4.9)
        Writing in front of others838 (87.5)97 (10.1)23 (2.4)

Data presented as n (%).

Fear of other things: no (n=900; 93.9%), a little (n=31; 3.2%), a lot (n=27; 2.8%).

Factor structure

The bifactor model with one general factor (fear) and two specific factors (specific and social) had the best fit (Table 2) as compared to other models (one-factor and correlated two-factor models). The bifactor model presented measurement invariance in multigroup CFA for age groups and gender (data not shown; available upon request). Therefore, further analysis were conducted using this model.
Table 2

Fit index of the one-dimensional, correlated, and bifactor models for specific and social fears

One-factorCorrelated two-factor Bifactor
FearSpecificSocialGSpecificSocial
Items
    Animals0.4590.524 0.2210.495
    Storms, thunder, heights0.5670.646 0.2620.62
    Dark0.5370.604 0.2590.566
    Blood, injection, injury0.5720.642 0.340.538
    Dentists, doctors0.560.613 0.4030.444
    Modes of transport0.5740.635 0.4020.476
    Enclosed spaces0.6080.677 0.370.563
    Toilets0.540.599 0.3560.473
    Monsters, etc.0.6080.68 0.3220.608
    Vomiting, choking, diseases0.5830.645 0.3880.502
    Loud noises0.6410.712 0.3440.632
    People who look unusual0.5510.612 0.3510.493
    Meeting new people0.639 0.7390.783 -0.239
    Meeting a lot of people0.695 0.80.89 -0.304
    Eating in front of others0.651 0.7530.804 -0.065
    Speaking in class0.751 0.8310.747 0.387
    Reading in front of others0.842 0.9180.727 0.657
    Writing in front of others0.851 0.8990.739 0.502
Fit indexes
    FP545572
    χ2 3,379.9 (df = 135; p < 0.001)898.2 (df = 134; p < 0.001)627.3 (df = 117; p < 0.001)
    RMSEA0.0980.0480.042
    90%CI0.095-0.1010.045-0.0510.038-0.045
    CFI0.7990.9530.968
    TLI0.7720.9460.959
    WRMR4.2422.0931.482
Reliability indexes
    Omega0.9210.8890.8700.9330.8890.945
    Omega h 0.600
    Omega s 0.6380.036

Data presented as factor loadings (λ).

90%CI = 90% confidence interval; CFI = comparative fit index; FP = fitting propensity; G = general factor; RMSEA = root mean square error of approximation; TLI = Tucker Lewis index; WRMR = weighted root mean square residual.

Investigating problem indicators

Factor loadings and category thresholds for the best-fitting CFA model (bifactor model with one general factor and two specific factors), as well as discrimination and severity parameters from the one-dimensional IRT model, are depicted in Table 3. Both CFA thresholds and IRT discrimination parameters converge to demonstrate that, generally, specific fears are more likely to be normative than social fears. For example, the mean of the severity parameter for specific fears was 1.77 (0.89-2.83), compared to 2.57 (1.74-3.39) for social fears in the IRT metric. The least severe specific fear (blood, injection, injury) had a location of 0.86, whereas the least severe social fear (reading in front of others) had a location of 1.74 (Table 3).
Table 3

Item response theory analysis for specific and social fears in the total sample (n=2,512)

Confirmatory factor analysis (bifactor model, general factor)Item response theory (unidimensional model)
Category thresholds Discrimination
Factor loadings (λ)A littleA lotLocation (mean)Location rankSlope (a)A little (b1)A lot (b2)Item location (mean b)Location rank
Specific fears
    Animals0.221-0.126 0.996 0.43510.942-0.254 2.048 0.8972
    Natural environments
        Storms, thunder, heights0.2620.103 1.133 0.61841.2860.168 1.885 1.02654
        Dark0.2590.025 0.978 0.50221.120.033 1.766 0.89953
    Blood, injection, injury
        Blood, injection, injury0.340.029 1.017 0.52331.2910.044 1.677 0.86051
        Dentists, doctors0.4030.535 1.392 0.96461.2180.904 2.426 1.6656
    Situational
        Modes of transport0.402 1.356 2.081 1.719151.444 2.116 3.382 2.74913
        Enclosed spaces0.37 1.109 1.849 1.479121.52 1.666 2.872 2.26912
        Toilets0.356 1.300 2.024 1.662131.316 2.153 3.493 2.82314
    Other fears
        Monsters etc.0.3220.533 1.384 0.95951.4140.823 2.191 1.5075
        Vomiting, choking, diseases0.3880.770 1.610 1.19081.4141.196 2.575 1.88559
        Loud noises0.344 0.886 1.643 1.26591.5841.299 2.469 1.8848
        People who look unusual0.351 1.379 2.024 1.702141.357 2.243 3.417 2.8315
Social fears
    Not restricted to performance
        Meeting new people0.783 1.632 2.449 2.041181.409 2.626 4.165 3.395518
        Meeting a lot of people0.89 1.524 2.259 1.892161.644 2.234 3.431 2.832516
        Eating in front of others0.804 1.506 2.449 1.978171.555 2.278 3.917 3.097517
    Performance only
        Speaking in class0.747 0.806 1.811 1.309101.3991.262 2.95 2.10610
        Reading in front of others0.7270.566 1.551 1.05971.330.913 2.571 1.7427
        Writing in front of others0.739 1.041 1.871 1.456111.504 1.576 2.921 2.248511

All items loaded significantly on their respective latent factors (p < 0.0001).

Threshold limits: 0.78 in confirmatory factor analysis and 1.53 in item response theory.

Bold indicates problem indicators.

Among specific fears, animals, natural environments, blood, injection, injury, and some fears classified as others (monsters; vomiting, choking, and diseases), were found to be normative when mild. Situational fears (modes of transport, enclosed spaces, and toilets) and fear of people who look unusual do indicate problems even when mild. All specific fears indicate problems when pervasive. Among social fears, those classified as performance-related only (speaking in class and reading in front of others) were found to be normative when graded as a little. Fears not restricted to performance (meeting new people, meeting a lot of people, and eating in front of others) and fear of writing in front of others do indicate problems even when mild. As in specific fears, all social fears indicate problems when pervasive. As an example, Figure 1 depicts item response function curves for one item classified as normative (Figure 1A) and one item classified as a problem indicator (Figure 1B). As shown in panel A, fear of blood, injection, and injury starts to be endorsed as a little for subjects at the mild end of the fear latent trait continuum, whereas only when classified as a lot is the item more likely to be endorsed by those at the severe end of the latent trait. In contrast, panel B shows that, for fear of meeting new people, the category a little starts to be endorsed by subjects already at the severe end of the fear spectrum whereas those endorsing the a lot category are at the extreme end of the latent trait spectrum.
Figure 1

Illustrative item response functions. A) Normative fear; B) Problem indicator

Investigating diagnostic indicators

Only fears characterized as a lot were evaluated in this analysis, because at least one of them is required for diagnosis of specific and social phobia. Our analysis showed that social fears tend to be more associated with phobias than specific fears. The AUC was nominally higher for social fears predicting social phobia than for specific fears predicting specific phobia: 0.775 (0.666-0.923) and 0.609 (0.525-0.731), respectively (Table 4).
Table 4

Associations between each specific and social fear classified as a lot with specific phobia and social phobia diagnosis in the total sample (n=2,512)

SnSpCCLR+LR-ROC95%CI
Specific fears
    Animals41.68583.42.80.70.6560.597-0.715
    Natural environments
        Storms, thunder, heights37.18886.23.10.70.6540.595-0.714
        Dark55.185843.70.50.7310.677-0.785
    Blood, injection, injury
        Blood, injection, injury38.285.483.72.60.70.6430.584-0.702
        Dentists, doctors20.292.289.72.60.90.6120.556-0.668
    Situational
        Modes of transport5.698.3953.210.5480.507-0.589
        Enclosed spaces6.796.993.72.210.5250.484-0.567
        Toilets13.598.395.37.80.90.5870.540-0.635
    Others
        Monsters, etc.29.292.590.23.90.80.6420.583-0.700
        Vomiting, choking, diseases12.394.9922.40.90.5870.534-0.639
        Loud noises16.995.492.63.70.90.5850.532-0.637
        People who look unusual10.198.1955.40.90.5460.505-0.586
Social fears
    Not restricted to performance
        Meeting new people23.199.598.747.80.80.7690.671-0.867
        Meeting a lot of people30.899.198.434.80.70.6880.588-0.789
        Eating in front of others19.299.598.736.80.80.6660.567-0.763
    Performance only
        Speaking in class57.797.196.719.60.40.830.735-0.924
        Reading aloud in front of others76.994.794.114.50.20.9230.873-0.972
        Writing in front of others46.297.496.917.70.50.7790.678-0.880

95%CI = 95% confidence interval; CC = correlation coefficient; LR+ = positive likelihood ratio; LR- = negative likelihood ratio; ROC = receiver operating characteristic curve; Sn = sensitivity; Sp = specificity.

Fears ordered by DSM-5 classification.

An inspection of each specific fear showed that, of 12 common fears graded as a lot, two yielded LR+ considered useful for diagnosis (LR+ > 5): toilets and people who look unusual. For all social fears classified as a lot, the LR+ was greater than 10 (17.7-47.8), indicating that screened positives are more likely than screened negatives to be confirmed as cases of social phobia. There was low sensitivity, particularly among specific fears (5.6-55.1), indicating a low proportion of truly positive individuals among those diagnosed with specific phobia. The sensitivity increased for social fears, especially for performance-only fears (46.2-76.9) (Table 4).

Discussion

To our knowledge, this is the first report to characterize the normal/abnormal spectrum of fears clinically and psychometrically in a community sample of children and youths. Our main findings are summarized as follows. First, specific fears are generally less likely to indicate problems and less likely to indicate a phobia diagnosis than social fears. Second, there is heterogeneity in the severity of both specific and social fears. Specific fears are generally not problematic when mild but become problematic when pervasive, and some are strongly indicative of specific phobia (i.e., fear of toilets and of people who look unusual). In contrast, most social fears indicate problems at both mild and severe levels, except for speaking in class and reading aloud in front of others, which appear to be normative at mild levels. In contrast, all social fears answered as pervasive were strongly indicative of a social phobia diagnosis. The developmental psychopathology framework theorizes that clinical patterns can be seen as deviations from normative patterns.31,32 The fear system matures in the beginning of infant development; as a consequence, normative fears are commonly present since very early in life.5,33,34 Our data showed that common fears occur in most children and adolescents, and it is their intensity that differentiates normative from clinically salient manifestations. In our results, the greater severity of social fears in comparison with specific fears was noteworthy. This is consistent with prior studies10,18 evaluating the clinical correlates of specific and social phobias in the same population of adolescents. In these studies, social phobia was more impairing, with worse rates on the Sheehan disability scale and days out of role.10,18 Furthermore, there is evidence that social phobia is more comorbid than specific phobia.9 With respect to specific fears, our results are in agreement with Burstein et al.,7 suggesting that the clinical relevance of specific phobia varies as a function of the nature of fears. However, the clinical significance found in Burstein et al.7 was somewhat different from that found in our sample. While both studies showed that fear of animals tends to be normative when present at mild levels and fear of enclosed spaces tends to indicate problems, our study found that fear of the dark and fears of blood, injection, and injury tend to be normative, whereas Burstein et al.7 showed that such fears were associated with greater severity. Our study is also aligned with others showing that situational phobia (fear of modes of transport, enclosed spaces, and toilets) is associated with high treatment-seeking behavior, use of medications, and interference with daily and social life,35 as well as higher level of comorbidity with other mental disorders36,37 in comparison with other types of specific phobia. In addition, we showed greater severity associated with fear of people who look unusual, which has been studied only rarely in the previous literature. With respect to social fears, contrasting fears not restricted to performance and those related to the performance only, comorbidities were most common in subjects with fears unrestricted to performance than in subjects with fears restricted to performance.9 Burstein et al.10 showed that anxiety about non-performance situations is associated with greater morbidity and clinical severity, earlier onset, and higher degree of disability and impairment if compared to performance fears, which is in agreement with our findings. As the odds of social fear related to performance increases with age, performance fears may only become clinically significant in adulthood, given that such fears are not of high developmental salience at the youngest age range of this sample.10 Limitations of this work must be noted. First, the questionnaires we used came from the specific fear and social fears sections of the DAWBA; therefore, our item pool was constrained by this measure. Also, our work was not designed specifically to capture developmental variations in fear expression, given that the scale employed uses subjective ratings (a little, a lot) rather than frequency scales, which might have limited our sensitivity to developmental variations. Nevertheless, we have a comprehensive list of fears, and the subjective ratings assigned might provide the opportunity to compare fears more directly across different age groups. Second, our analysis was restricted to parent-reported fears, and parents might not be aware of their children’s fears if the latter do not express them explicitly. However, specific and social fears have been shown to be captured more similarly by parent and child reports, if compared to other forms of anxiety.38 Third, our analysis was restricted to cross-sectional associations, and important severity validators, such as persistence, could not be analyzed. Finally, to answer the complete DAWBA specific fear and social fears sections, the subject must have at least one specific fear graded as a lot (a condition also required for diagnosis); therefore, we were unable to use ROC analysis for fears classified as a little. Advancing understanding about the boundaries between normative symptoms and problem indicators is a major concern in child and adolescent psychiatry practice. Our findings are a first step towards defining parameters to alert clinicians of when to be, and when not to be, concerned with specific and social fears. Furthermore, we provide insights into the dimensionality of the fear trait, showing that not all fears are created equally, i.e., they vary widely in terms of severity and might carry different information about typical vs. atypical development. Our results also indicate that severity-based classification of fears provides clinically useful information for the diagnosis of specific and social phobia. Future research examining these patterns with measures specifically designed to differentiate normative versus non-normative patterns, and including developmentally sensitive items, might be an important path to advancing the field. Prospective longitudinal investigations that apply this framework beginning at earlier ages may be able to elucidate the origins of pathologic fear pathways and inform developmentally based prevention.

Disclosure

LAR has been on the speakers’ bureau and/or has acted as consultant for Eli Lilly, Janssen-Cilag, Novartis, and Shire over the last 3 years. The ADHD and Juvenile Bipolar Disorder Outpatient Programs chaired by him have received unrestricted educational and research support from Eli Lilly, Janssen-Cilag, Novartis, and Shire in the last 3 years. He received travel grants from Shire to take part in the 2014 APA and 2015 WFADHD meetings. He also receives authorship royalties from Oxford University Press and Artmed. The other authors report no conflicts of interest.
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Review 5.  Childhood antecedents and risk for adult mental disorders.

Authors:  Daniel S Pine; Nathan A Fox
Journal:  Annu Rev Psychol       Date:  2015-01-03       Impact factor: 24.137

6.  Which fearful toddlers should we worry about? Context, fear regulation, and anxiety risk.

Authors:  Kristin A Buss
Journal:  Dev Psychol       Date:  2011-05

7.  The prevalence and comorbidity of social anxiety disorder among United States Latinos: a retrospective analysis of data from 2 national surveys.

Authors:  Antonio J Polo; Margarita Alegría; Chih-Nan Chen; Carlos Blanco
Journal:  J Clin Psychiatry       Date:  2011-08       Impact factor: 4.384

8.  Specific fears and phobias in the general population: results from the Netherlands Mental Health Survey and Incidence Study (NEMESIS).

Authors:  Marja F I A Depla; Margreet L ten Have; Anton J L M van Balkom; Ron de Graaf
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2007-11-30       Impact factor: 4.328

9.  Social fears and social phobia in the USA: results from the National Comorbidity Survey Replication.

Authors:  A M Ruscio; T A Brown; W T Chiu; J Sareen; M B Stein; R C Kessler
Journal:  Psychol Med       Date:  2007-11-02       Impact factor: 7.723

Review 10.  Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice.

Authors:  Giovanni Abrahão Salum; Diogo Araújo Desousa; Maria Conceição do Rosário; Daniel Samuel Pine; Gisele Gus Manfro
Journal:  Braz J Psychiatry       Date:  2013       Impact factor: 2.697

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1.  Fearful Temperament and Child Social Anxiety Symptoms: Clarifying the Influence of Maternal Punitive Responses.

Authors:  Erika S Trent; Andres G Viana; Elizabeth M Raines; Haley E Conroy; Emma C Woodward; Eric A Storch; Michael J Zvolensky
Journal:  Res Child Adolesc Psychopathol       Date:  2021-02-23
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