| Literature DB >> 28300286 |
Afsane Bahrami1, Malihe Hasanzadeh2, Soodabeh ShahidSales3, Zohre Yousefi2, Sima Kadkhodayan2, Marjaneh Farazestanian2, Mona Joudi Mashhad3, Masoumeh Gharib4, Seyed Mahdi Hassanian5,6, Amir Avan6.
Abstract
Cervical cancer is among the most commonly diagnosed cancer in women, supporting the need for identification of novel prognostic and predictive biomarkers to predict the risk of developing of this malignancy or predict the prognosis of patients. Against this background, the activation of the Wingless-type (Wnt)/β-catenin pathway has been suggested as the main dysregulated pathways, which is involved in the multistep process of cervical carcinogenesis, suggesting its value as a potential biomarker or therapeutic target. The aim of current review is to give an overview about the potential application of WNT pathway and its value which is differentially expressed in cervical cancer versus non-tumorigenic tissue as biomarker for risk stratification and predict the prognosis of patients with cervical cancer. J. Cell. Biochem. 118: 3028-3033, 2017.Entities:
Keywords: CERVICAL CANCER; PATIENTS; WNT PATHWAY
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Year: 2017 PMID： 28300286 DOI： 10.1002/jcb.25992
Source DB: PubMed Journal: J Cell Biochem ISSN： 0730-2312 Impact factor: 4.429