Literature DB >> 28299931

Synthesis of Amides and Nitriles from Vinyl Azides and p-Quinone Methides.

Chen Lin1, Yangyong Shen1, Bo Huang1, Yu Liu2, Sunliang Cui1.   

Abstract

A divergent synthesis of amides and nitriles from vinyl azides and p-quinone methides (p-QMs) was developed. The p-QMs could be activated by BF3-Et2O and then nucleophilically attacked by vinyl azides, leading to divergent rearrangement toward amides and nitriles.

Entities:  

Year:  2017        PMID: 28299931     DOI: 10.1021/acs.joc.7b00145

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

1.  Vinyl Azides as Radical Acceptors in the Vitamin B12-Catalyzed Synthesis of Unsymmetrical Ketones.

Authors:  Krzysztof R Dworakowski; Sabina Pisarek; Sidra Hassan; Dorota Gryko
Journal:  Org Lett       Date:  2021-11-16       Impact factor: 6.005

  1 in total

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