Vinod Kumar1, Devesh Kumawat2. 1. Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, 110029, India. drvinod_agg@yahoo.com. 2. Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, 110029, India.
Abstract
AIMS: To report multi-modal imaging findings in a case of butterfly pattern dystrophy of retinal pigment epithelium. METHODS: A middle-aged female with butterfly pattern dystrophy, who presented with progressive loss of vision, was examined using coloured fundus photographs, short wave autofluorescence, swept source optical coherence tomography (SS-OCT), fundus fluorescein angiography and enface optical coherence tomography. RESULTS: Multi-modal imaging was useful in the characterization of the various disease features. Autofluorescence pattern was opposite to that of fluorescein angiogram and SS-OCT showed disruption in the outer retinal layers. Enface OCT images depicted the pigment deposition prominently. CONCLUSION: The features of butterfly pattern dystrophy on these modalities correlated well with the histopathological findings described in the literature. Enface imaging highlights the deposition of pigment/lipofuscin and has never been described in BPD.
AIMS: To report multi-modal imaging findings in a case of butterfly pattern dystrophy of retinal pigment epithelium. METHODS: A middle-aged female with butterfly pattern dystrophy, who presented with progressive loss of vision, was examined using coloured fundus photographs, short wave autofluorescence, swept source optical coherence tomography (SS-OCT), fundus fluorescein angiography and enface optical coherence tomography. RESULTS: Multi-modal imaging was useful in the characterization of the various disease features. Autofluorescence pattern was opposite to that of fluorescein angiogram and SS-OCT showed disruption in the outer retinal layers. Enface OCT images depicted the pigment deposition prominently. CONCLUSION: The features of butterfly pattern dystrophy on these modalities correlated well with the histopathological findings described in the literature. Enface imaging highlights the deposition of pigment/lipofuscin and has never been described in BPD.
Authors: Nicole T M Saksens; Mark P Krebs; Frederieke E Schoenmaker-Koller; Wanda Hicks; Minzhong Yu; Lanying Shi; Lucy Rowe; Gayle B Collin; Jeremy R Charette; Stef J Letteboer; Kornelia Neveling; Tamara W van Moorsel; Sleiman Abu-Ltaif; Elfride De Baere; Sophie Walraedt; Sandro Banfi; Francesca Simonelli; Frans P M Cremers; Camiel J F Boon; Ronald Roepman; Bart P Leroy; Neal S Peachey; Carel B Hoyng; Patsy M Nishina; Anneke I den Hollander Journal: Nat Genet Date: 2015-12-21 Impact factor: 38.330