Literature DB >> 28298056

Outcomes After Biologically Augmented Isolated Meniscal Repair With Marrow Venting Are Comparable With Those After Meniscal Repair With Concomitant Anterior Cruciate Ligament Reconstruction.

Chase S Dean1, Jorge Chahla1, Lauren M Matheny1, Justin J Mitchell1, Robert F LaPrade1,2.   

Abstract

BACKGROUND: Meniscal repair in the setting of anterior cruciate ligament (ACL) reconstruction has demonstrated superior outcomes compared with isolated meniscal repair. Limited evidence exists for the effects of biological augmentation in isolated meniscal repair, particularly as compared with meniscal repair with concomitant ACL reconstruction. Purpose/Hypothesis: The purpose of this study was to compare the outcomes and survivorship of meniscal repair in 2 cohorts of patients: meniscal repair with biological augmentation using a marrow venting procedure (MVP) of the intercondylar notch, and meniscal repair with concomitant ACL reconstruction. We hypothesized that the clinical outcomes and survivorship of meniscal repair with concomitant ACL reconstruction would be improved compared with meniscal repair with biological augmentation. STUDY
DESIGN: Cohort study; Level of evidence, 3.
METHODS: Inclusion criteria were skeletally mature patients aged ≥16 years who underwent inside-out meniscal repair and either a concomitant MVP of the intercondylar notch or ACL reconstruction. Patients were excluded from this study if they were skeletally immature, underwent meniscus root or radial tear repair, or underwent meniscal repair with concurrent ligamentous reconstruction not limited to the ACL. At the preoperative evaluation and a minimum 2 years after the index meniscal repair procedure, patients were administered a subjective questionnaire. Differences in outcome scores, survivorship, and failure rates between the cohorts were assessed. Failure was defined as reoperation with meniscectomy or revision meniscal repair.
RESULTS: There were 109 patients (52 female, 57 male) who met the inclusion criteria for this study. There were 37 knees in cohort 1 (isolated meniscal repair plus MVP) and 72 knees in cohort 2 (meniscal repair plus ACL reconstruction). The failure status was known in 95 patients, and patient-reported outcome scores were obtained in 89 (82%) patients. Both cohorts demonstrated a significant improvement in all outcome scores, and there was no significant difference in any of the preoperative or postoperative outcome measures. The overall failure rate was 9.5% (9/95). There were 4 (12.9%) failures in cohort 1 and 5 failures (7.8%) in cohort 2, with no significant difference in failures between the cohorts ( P = .429). There was a significant association between failure and female sex ( P = .001).
CONCLUSION: The most important finding in this study was that there was no difference in outcomes in meniscal repair performed with biological augmentation using an MVP versus that performed concomitantly with ACL reconstruction. The similar outcomes reported for meniscal repair with an MVP and meniscal repair with ACL reconstruction may be partly attributed to biological augmentation.

Entities:  

Keywords:  ACL reconstruction; biological augmentation; inside-out repair; marrow stimulation; meniscal repair; patient-reported outcomes; vertical mattress suture

Mesh:

Year:  2017        PMID: 28298056     DOI: 10.1177/0363546516686968

Source DB:  PubMed          Journal:  Am J Sports Med        ISSN: 0363-5465            Impact factor:   6.202


  13 in total

Review 1.  Meniscal repair and regeneration: Current strategies and future perspectives.

Authors:  Kazunori Shimomura; Shuichi Hamamoto; David A Hart; Hideki Yoshikawa; Norimasa Nakamura
Journal:  J Clin Orthop Trauma       Date:  2018-07-17

Review 2.  Surgical and tissue engineering strategies for articular cartilage and meniscus repair.

Authors:  Heenam Kwon; Wendy E Brown; Cassandra A Lee; Dean Wang; Nikolaos Paschos; Jerry C Hu; Kyriacos A Athanasiou
Journal:  Nat Rev Rheumatol       Date:  2019-07-11       Impact factor: 20.543

Review 3.  The Current Role of Biologics for Meniscus Injury and Treatment.

Authors:  Ian D Hutchinson; Scott A Rodeo
Journal:  Curr Rev Musculoskelet Med       Date:  2022-07-26

Review 4.  Does Anterior Cruciate Ligament Reconstruction Protect the Meniscus and Its Repair? A Systematic Review.

Authors:  Jasmijn V Korpershoek; Tommy S de Windt; Lucienne A Vonk; Aaron J Krych; Daniel B F Saris
Journal:  Orthop J Sports Med       Date:  2020-07-28

5.  Assessing the Resident Progenitor Cell Population and the Vascularity of the Adult Human Meniscus.

Authors:  Jorge Chahla; Angela Papalamprou; Virginia Chan; Yasaman Arabi; Khosrawdad Salehi; Trevor J Nelson; Orr Limpisvasti; Bert R Mandelbaum; Wafa Tawackoli; Melodie F Metzger; Dmitriy Sheyn
Journal:  Arthroscopy       Date:  2020-09-23       Impact factor: 4.772

Review 6.  Blood in the joint: effects of hemarthrosis on meniscus health and repair techniques.

Authors:  L P Lyons; J B Weinberg; J R Wittstein; A L McNulty
Journal:  Osteoarthritis Cartilage       Date:  2020-12-08       Impact factor: 6.576

Review 7.  Degenerative Meniscus in Knee Osteoarthritis: From Pathology to Treatment.

Authors:  Nobutake Ozeki; Hideyuki Koga; Ichiro Sekiya
Journal:  Life (Basel)       Date:  2022-04-18

8.  Inside-Out Repair of Meniscal Ramp Lesions.

Authors:  Nicholas N DePhillipo; Mark E Cinque; Nicholas I Kennedy; Jorge Chahla; Andrew G Geeslin; Gilbert Moatshe; Lars Engebretsen; Robert F LaPrade
Journal:  Arthrosc Tech       Date:  2017-08-14

Review 9.  Augmentation of Meniscal Repair With Platelet-Rich Plasma: A Systematic Review of Comparative Studies.

Authors:  John W Belk; Matthew J Kraeutler; Stephen G Thon; Connor P Littlefield; John H Smith; Eric C McCarty
Journal:  Orthop J Sports Med       Date:  2020-06-17

10.  The modified cross-suture technique for unilateral pulled-out anchor during all-inside meniscal repair.

Authors:  Jianlong Ni; Zhibin Shi; Lihong Fan; Ning Guo; Haoyu Wang; Xiaoqian Dang; Dichen Li
Journal:  BMC Musculoskelet Disord       Date:  2020-07-22       Impact factor: 2.362

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