Literature DB >> 28296401

Effects of Low-Protein Diets Supplemented with Branched-Chain Amino Acid on Lipid Metabolism in White Adipose Tissue of Piglets.

Yinghui Li1,2, Hongkui Wei3, Fengna Li1,4, Yehui Duan1,2, Qiuping Guo1,2, Yulong Yin1,5.   

Abstract

This study evaluated the effect of branched-chain amino acid (BCAA) supplementation in low-protein diets on lipid metabolism in dorsal subcutaneous adipose (DSA), abdominal subcutaneous adipose (ASA), and perirenal adipose (PRA) tissues. A total of 24 piglets were allotted to four treatments, and each group was fed the adequate protein (AP) diet, low-protein (LP) diet, LP diet supplemented with BCAA (LP + B), or LP diet supplemented with twice BCAA (LP + 2B). Serum concentrations of leptin in the BCAA-supplemented treatments were higher (P < 0.01) than in the AP treatment, but lower (P < 0.01) than in the LP treatment. In DSA, the mRNA and protein levels for lipogenic-related genes were highest in the LP treatment and lowest in the LP + 2B treatment. However, in ASA and PRA, the expression levels for those genes were significantly elevated in the LP + 2B treatment. In conclusion, BCAA supplementation could alter the body fat condition, and this effect was likely modulated by the expression of lipid metabolic regulators in DSA, ASA, and PRA in a depot-specific manner.

Entities:  

Keywords:  branched-chain amino acids; lipid metabolism; low-protein diet; piglet; white adipose tissue

Mesh：

Substances：

Year:  2017        PMID： 28296401     DOI： 10.1021/acs.jafc.7b00488

Source DB:  PubMed          Journal:  J Agric Food Chem        ISSN： 0021-8561            Impact factor:   5.279


  7 in total

1.  The Role of Gut Microbiota in the Skeletal Muscle Development and Fat Deposition in Pigs.

Authors:  Qi Han; Xingguo Huang; Fuyong Yan; Jie Yin; Yingping Xiao
Journal:  Antibiotics (Basel)       Date:  2022-06-11

2.  Camellia (Camellia oleifera Abel.) Seed Oil Regulating of Metabolic Phenotype and Alleviates Dyslipidemia in High Fat-Fed Mice through Serum Branch-Chain Amino Acids.

Authors:  Jing Gao; Li Ma; Jie Ma; Siting Xia; Saiming Gong; Yulong Yin; Yongzhong Chen
Journal:  Nutrients       Date:  2022-06-10       Impact factor: 6.706

3.  Repletion of branched chain amino acids reverses mTORC1 signaling but not improved metabolism during dietary protein dilution.

Authors:  Adriano Maida; Jessica S K Chan; Kim A Sjøberg; Annika Zota; Dieter Schmoll; Bente Kiens; Stephan Herzig; Adam J Rose
Journal:  Mol Metab       Date:  2017-06-24       Impact factor: 7.422

4.  Excessive BCAA regulates fat metabolism partially through the modification of m6A RNA methylation in weanling piglets.

Authors:  Jinghui Heng; Zhihui Wu; Min Tian; Jiaming Chen; Hanqing Song; Fang Chen; Wutai Guan; Shihai Zhang
Journal:  Nutr Metab (Lond)       Date:  2020-01-23       Impact factor: 4.169

5.  Effects of Dietary Crude Protein Levels on Fecal Crude Protein, Amino Acids Flow Amount, Fecal and Ileal Microbial Amino Acids Composition and Amino Acid Digestibility in Growing Pigs.

Authors:  Zhenguo Yang; Tianle He; Gifty Ziema Bumbie; Hong Hu; Qingju Chen; Changwen Lu; Zhiru Tang
Journal:  Animals (Basel)       Date:  2020-11-11       Impact factor: 2.752

6.  Effects of Dietary Protein Levels on Fecal Amino Acids Excretion and Apparent Digestibility, and Fecal and Ileal Microbial Amino Acids Composition in Weaned Piglets.

Authors:  Zhenguo Yang; Huan Deng; Tianle He; Zhihong Sun; Ziema Bumbie Gifty; Ping Hu; Zebing Rao; Zhiru Tang
Journal:  Front Nutr       Date:  2021-12-16

7.  Dietary supplementation with betaine or glycine improves the carcass trait, meat quality and lipid metabolism of finishing mini-pigs.

Authors:  Yinzhao Zhong; Zhaoming Yan; Bo Song; Changbing Zheng; Yehui Duan; Xiangfeng Kong; JinPing Deng; Fengna Li
Journal:  Anim Nutr       Date:  2021-02-27
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.