Literature DB >> 2829565

Complement-dependent neutralization of transmissible gastroenteritis virus by monoclonal antibodies.

R D Woods1, R D Wesley, P A Kapke.   

Abstract

Monoclonal antibodies (MAb) to each of the 3 major structural proteins of transmissible gastroenteritis virus (TGEV) of swine were compared as to their virus neutralizing activity in the presence or absence of guinea pig complement. MAbs to the peplomer protein had neutralizing activity for TGEV with or without complement and the titers were similar in either case. MAbs to the matrix protein had neutralizing activity for TGEV only in the presence of complement. Antibodies to the nucleocapsid protein were without neutralizing activity with or without complement. High concentrations of guinea pig complement, but not swine complement, had neutralizing activity for TGEV even in the absence of any known TGEV antibodies.

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Year:  1987        PMID: 2829565     DOI: 10.1007/978-1-4684-1280-2_64

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  13 in total

1.  The membrane M protein carboxy terminus binds to transmissible gastroenteritis coronavirus core and contributes to core stability.

Authors:  D Escors; J Ortego; H Laude; L Enjuanes
Journal:  J Virol       Date:  2001-02       Impact factor: 5.103

2.  Epitope specificity of protective lactogenic immunity against swine transmissible gastroenteritis virus.

Authors:  M De Diego; M D Laviada; L Enjuanes; J M Escribano
Journal:  J Virol       Date:  1992-11       Impact factor: 5.103

3.  Membrane protein molecules of transmissible gastroenteritis coronavirus also expose the carboxy-terminal region on the external surface of the virion.

Authors:  C Risco; I M Antón; C Suñé; A M Pedregosa; J M Martín-Alonso; F Parra; J L Carrascosa; L Enjuanes
Journal:  J Virol       Date:  1995-09       Impact factor: 5.103

4.  Recombinant M protein-based ELISA test for detection of antibodies to canine coronavirus.

Authors:  Gabriella Elia; Giuseppe Fiermonte; Annamaria Pratelli; Vito Martella; Michele Camero; Francesco Cirone; Canio Buonavoglia
Journal:  J Virol Methods       Date:  2003-05       Impact factor: 2.014

5.  Expression of swine transmissible gastroenteritis virus envelope antigens on the surface of infected cells: epitopes externally exposed.

Authors:  M D Laviada; S P Videgain; L Moreno; F Alonso; L Enjuanes; J M Escribano
Journal:  Virus Res       Date:  1990-07       Impact factor: 3.303

6.  Vaccines to prevent severe acute respiratory syndrome coronavirus-induced disease.

Authors:  Luis Enjuanes; Marta L Dediego; Enrique Alvarez; Damon Deming; Tim Sheahan; Ralph Baric
Journal:  Virus Res       Date:  2007-04-09       Impact factor: 3.303

7.  High-level prokaryotic expression of envelope exterior of membrane protein of porcine epidemic diarrhea virus.

Authors:  Gao Shenyang; Zha Enhui; Li Baoxian; Qiao Xinyuan; Tang Lijie; Ge Junwei; Li Yijing
Journal:  Vet Microbiol       Date:  2007-03-30       Impact factor: 3.293

8.  The expression of SARS-CoV M gene in P. Pastoris and the diagnostic utility of the expression product.

Authors:  Xueqing Han; Mark Bartlam; Ying-Hua Jin; Xiangtao Liu; Xiaojing He; Xuepeng Cai; Qingqe Xie; Zihe Rao
Journal:  J Virol Methods       Date:  2004-12-01       Impact factor: 2.014

9.  Identification of coronaviruses in dogs that segregate separately from the canine coronavirus genotype.

Authors:  Annamaria Pratelli; Vito Martella; Mauro Pistello; Gabriella Elia; Nicola Decaro; Domenico Buonavoglia; Michele Camero; Maria Tempesta; Canio Buonavoglia
Journal:  J Virol Methods       Date:  2003-02       Impact factor: 2.014

10.  Safety and efficacy of a modified-live canine coronavirus vaccine in dogs.

Authors:  A Pratelli; A Tinelli; N Decaro; V Martella; M Camero; M Tempesta; M Martini; L E Carmichael; C Buonavoglia
Journal:  Vet Microbiol       Date:  2004-03-26       Impact factor: 3.293

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