Literature DB >> 28295361

Smoking: An independent risk factor for lost productivity in chronic rhinosinusitis.

Adam P Campbell1,2, Lloyd P Hoehle1,2, Katie M Phillips1,2, David S Caradonna1,3, Stacey T Gray1,2, Ahmad R Sedaghat1,2,3,4.   

Abstract

OBJECTIVES/HYPOTHESIS: Chronic rhinosinusitis (CRS) is associated with a significant loss of patient productivity that costs billions of dollars every year. Smoking is associated with worsening sinonasal symptoms, but its effect on lost productivity in CRS patients has yet to be described. Therefore, we sought to determine the association between smoking and productivity in patients with CRS. STUDY
DESIGN: Prospective cross-sectional cohort study of 140 patients with CRS.
METHODS: Sinonasal symptom severity was measured using the 22-item Sino-Nasal Outcomes Test. Lost productivity was assessed by asking participants how many days of work and/or school they missed in the last 3 months due to CRS. Associations were sought between lost productivity and smoking.
RESULTS: Participants missed a mean of 3.0 days (standard deviation = 12.8 days) of work or school due to CRS. Having any history of smoking was associated with 6 days of lost productivity due to CRS (adjusted β = 6.20, 95% confidence interval [CI]: 0.64 to 11.77, P = .031). Although the number of active smokers in our study cohort was very small (N = 6), we performed a univariate association between smoking status, considering former smokers and active smokers separately, and found that active smoking (β = 11.75, 95% CI: 2.11 to 21.40, P = .018) had a much larger impact on CRS-related productivity loss than that experienced by former smokers (β = 4.45, 95% CI: -0.32 to 9.23, P = .070).
CONCLUSIONS: Smoking (likely driven by active smoking) is independently associated with missed days of work or school in patients with CRS. Further study is needed to determine whether interventions directed at smoking may impact CRS-related productivity loss. LEVEL OF EVIDENCE: 2c Laryngoscope, 127:1742-1745, 2017.
© 2017 The American Laryngological, Rhinological and Otological Society, Inc.

Entities:  

Keywords:  Smoking; chronic rhinosinusitis; productivity; quality of life; tobacco

Mesh:

Year:  2017        PMID: 28295361     DOI: 10.1002/lary.26548

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  6 in total

1.  Workplace Indirect Cost Impacts of Nasal and Sinus Symptoms and Related Conditions.

Authors:  Jordan R Kuiper; Annemarie G Hirsch; Karen Bandeen-Roche; Agnes S Sundaresan; Bruce K Tan; Robert C Kern; Robert P Schleimer; Brian S Schwartz
Journal:  J Occup Environ Med       Date:  2019-08       Impact factor: 2.162

2.  Longitudinal improvement in nasal obstruction symptoms of chronic rhinosinusitis directly associates with improvement in mood.

Authors:  Marlene M Speth; Katie M Phillips; Lloyd P Hoehle; David S Caradonna; Stacey T Gray; Ahmad R Sedaghat
Journal:  Eur Arch Otorhinolaryngol       Date:  2019-07-19       Impact factor: 2.503

3.  Seasonal variations in chronic rhinosinusitis symptom burden may be explained by changes in mood.

Authors:  Rehab Talat; Katie M Phillips; David S Caradonna; Stacey T Gray; Ahmad R Sedaghat
Journal:  Eur Arch Otorhinolaryngol       Date:  2019-07-15       Impact factor: 2.503

4.  MicroRNA-761 suppresses remodeling of nasal mucosa and epithelial-mesenchymal transition in mice with chronic rhinosinusitis through LCN2.

Authors:  Jinzhang Cheng; Junjun Chen; Yin Zhao; Jingpu Yang; Kai Xue; Zonggui Wang
Journal:  Stem Cell Res Ther       Date:  2020-04-09       Impact factor: 6.832

5.  Tobacco Smoking Could Accentuate Epithelial-Mesenchymal Transition and Th2-Type Response in Patients With Chronic Rhinosinusitis With Nasal Polyps.

Authors:  Ki-Il Lee; Younghwan Han; Jae-Sung Ryu; Seung Min In; Jong-Yeup Kim; Joong Su Park; Jong-Seok Kim; Juhye Kim; Jubin Youn; Seok-Rae Park
Journal:  Immune Netw       Date:  2022-06-15       Impact factor: 5.851

6.  Chronic rhinosinusitis control from the patient and physician perspectives.

Authors:  Ahmad R Sedaghat; Lloyd P Hoehle; Stacey T Gray
Journal:  Laryngoscope Investig Otolaryngol       Date:  2018-10-09
  6 in total

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