Literature DB >> 28295238

IL-17 and IL-22 in immunity: Driving protection and pathology.

Kilian Eyerich1, Valentina Dimartino2, Andrea Cavani2.   

Abstract

IL-17 and IL-22 are tissue-signaling cytokines that favor protection and regeneration of barrier organs such as the skin, lung, and gastrointestinal system. Both cytokines share cellular sources, signaling pathways, and functional aspects; however, taking a closer look they differ, e.g. in their pro-inflammatory or regenerative potential. An imbalance of the carefully orchestrated tissue-signaling system might result in autoimmune diseases, promote cancer growth, or predispose to infectious diseases. This review highlights recent understandings in cellular sources, signaling mechanisms, physiologic as well as pathogenic role of the double-faceted cytokines IL-17 and IL-22.
© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Th17; Th22; autoimmune diseases; cytokines

Mesh：

Substances：

Year:  2017        PMID： 28295238     DOI： 10.1002/eji.201646723

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  109 in total

1.  IL-17 Promotes Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas.

Authors:  Rao Me; Nan Gao; Chenyang Dai; Fu-Shin X Yu
Journal:  J Immunol       Date:  2019-11-25       Impact factor: 5.422

2.  Spatial distribution of LTi-like cells in intestinal mucosa regulates type 3 innate immunity.

Authors:  Cristiane Sécca; Jennifer K Bando; José L Fachi; Susan Gilfillan; Vincent Peng; Blanda Di Luccia; Marina Cella; Keely G McDonald; Rodney D Newberry; Marco Colonna
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Review 3.  Homeostatic Immunity and the Microbiota.

Authors:  Yasmine Belkaid; Oliver J Harrison
Journal:  Immunity       Date:  2017-04-18       Impact factor: 31.745

4.  G protein-coupled receptor kinase-2-deficient mice are protected from dextran sodium sulfate-induced acute colitis.

Authors:  Michael D Steury; Ho Jun Kang; Taehyung Lee; Peter C Lucas; Laura R McCabe; Narayanan Parameswaran
Journal:  Physiol Genomics       Date:  2018-03-23       Impact factor: 3.107

Review 5.  HIV and the Gut Microbiota: Composition, Consequences, and Avenues for Amelioration.

Authors:  Ivan Vujkovic-Cvijin; Ma Somsouk
Journal:  Curr HIV/AIDS Rep       Date:  2019-06       Impact factor: 5.071

6.  Cytokines, growth factors and proteases in medium and large vessel vasculitis.

Authors:  Cornelia M Weyand; Ryu Watanabe; Hui Zhang; Mitsuhiro Akiyama; Gerald J Berry; Jörg J Goronzy
Journal:  Clin Immunol       Date:  2019-02-14       Impact factor: 3.969

7.  Functional Perturbation of Mucosal Group 3 Innate Lymphoid and Natural Killer Cells in Simian-Human Immunodeficiency Virus/Simian Immunodeficiency Virus-Infected Infant Rhesus Macaques.

Authors:  Brady Hueber; Alan D Curtis; Kyle Kroll; Valerie Varner; Rhianna Jones; Sachi Pathak; Michelle Lifton; Koen K A Van Rompay; Kristina De Paris; R Keith Reeves
Journal:  J Virol       Date:  2020-02-14       Impact factor: 5.103

8.  An Isolated TCR αβ Restricted by HLA-A*02:01/CT37 Peptide Redirecting CD8+ T Cells To Kill and Secrete IFN-γ in Response to Lung Adenocarcinoma Cell Lines.

Authors:  Pedro O Flores-Villanueva; Malathesha Ganachari; Heinner Guio; Jaime A Mejia; Julio Granados
Journal:  J Immunol       Date:  2018-03-19       Impact factor: 5.422

9.  Betamethasone Treatment for Atopic Dermatitis in Gut Microbiota Transplanted Mice.

Authors:  Karina P Debes; Nathalie A Evdina; Ann Laigaard; Julie M Larsen; Line F Zachariassen; Camilla H F Hansen; Axel K Hansen
Journal:  Comp Med       Date:  2019-11-19       Impact factor: 0.982

Review 10.  T Cell Cytokines Impact Epithelial Cell Responses during Helicobacter pylori Infection.

Authors:  Holly M Scott Algood
Journal:  J Immunol       Date:  2020-03-15       Impact factor: 5.422
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