Literature DB >> 28294350

High-resolution fiber-optic dosimeters for microbeam radiation therapy.

James Archer1, Enbang Li1, Marco Petasecca1, Michael Lerch1, Anatoly Rosenfeld1, Martin Carolan2.   

Abstract

PURPOSE: A high resolution, water equivalent, optical and passive x-ray dosimeter has been constructed using plastic scintillator and optical fiber. This dosimeter has a peak edge-on spatial resolution of 100 μm in one dimension, with a 10 μm resolution dosimeter under investigation. The dosimeter design has a potential application in synchrotron x-ray microbeam radiation therapy where a high resolution is vital for accurate dose measurements and quality assurance.
METHODS: BC-400 plastic scintillator, of thickness 100 μm, was optically coupled to an optical fiber with core diameter 1 mm. The end was coated in optical paint to improve sensitivity. An identical fiber was made without the scintillator to measure the background Cherenkov radiation induced in the fiber, to allow background signal subtraction. The light captured by the fibers was measured by PMTs. The probe system was exposed to a 6 MV, 10 × 10 cm2 LINAC x-ray field and the beam profile was measured at 100 cm, as well as the depth dose profile.
RESULTS: The measured profiles matched well with ionisation chamber data. Important beam parameters such as penumbra width and percent depth dose at various depths matched the ionisation chamber data, within uncertainty.
CONCLUSIONS: This work demonstrates that high resolutions can be achieved with a scintillation and optical fiber system. The probe is water-equivalent, passive, energy independent, radiation hard and inexpensive, making it ideal for further improvements for use with microbeam radiation therapy.
© 2017 American Association of Physicists in Medicine.

Entities:  

Keywords:  fiber-optic dosimetry; microbeam radiation therapy; scintillators; x-ray

Mesh:

Year:  2017        PMID: 28294350     DOI: 10.1002/mp.12209

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  2 in total

1.  Pixel Image Analysis and Its Application with an Alcohol-Based Liquid Scintillator for Particle Therapy.

Authors:  Ji-Won Choi; Ji-Young Choi; Hanil Jang; Kyung-Kwang Joo; Byoung-Chan Kim
Journal:  Sensors (Basel)       Date:  2022-06-28       Impact factor: 3.847

2.  X-ray microbeam measurements with a high resolution scintillator fibre-optic dosimeter.

Authors:  James Archer; Enbang Li; Marco Petasecca; Andrew Dipuglia; Matthew Cameron; Andrew Stevenson; Chris Hall; Daniel Hausermann; Anatoly Rosenfeld; Michael Lerch
Journal:  Sci Rep       Date:  2017-09-29       Impact factor: 4.379

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.