Literature DB >> 28292719

Donor age matters in T-cell depleted haploidentical hematopoietic stem cell transplantation in pediatric patients: Faster immune reconstitution using younger donors.

Marta González-Vicent1, Blanca Molina2, Natalia Deltoro2, Julián Sevilla3, José Luis Vicario4, Ana Castillo5, Manuel Ramirez5, Miguel Ángel Díaz2.   

Abstract

T-cell depleted (TCD) haploidentical transplantation is increasingly used in paediatric patients with haematological malignancies and donor selection is a challenge. We conclude that a simple criterion such as donor age should be also considered in depleted haploidentical setting because faster immune reconstitution is achieved using younger donors decreasing non-relapse related mortality. Published by Elsevier Ltd.

Entities:  

Keywords:  Donor age; HSCT; Haploidentical; Immune reconstitution; Pediatric; T-cell depletion

Mesh：

Year:  2017        PMID： 28292719     DOI： 10.1016/j.leukres.2017.03.001

Source DB:  PubMed          Journal:  Leuk Res        ISSN： 0145-2126            Impact factor:   3.156


  9 in total

Review 1.  The role of the thymus in allogeneic bone marrow transplantation and the recovery of the peripheral T-cell compartment.

Authors:  Enrico Velardi; Emmanuel Clave; Franco Locatelli; Antoine Toubert; Lucas C M Arruda; Francesca Benini
Journal:  Semin Immunopathol       Date:  2021-01-08       Impact factor: 9.623

2.  CD4+ T-cell reconstitution predicts survival outcomes after acute graft-versus-host-disease: a dual-center validation.

Authors:  Coco de Koning; Susan Prockop; Ichelle van Roessel; Nancy Kernan; Elizabeth Klein; Jurgen Langenhorst; Celina Szanto; Mirjam Belderbos; Marc Bierings; Farid Boulad; Dorine Bresters; Maria Cancio; Kevin Curran; Wouter Kollen; Richard O'Reilly; Andromachi Scaradavou; Barbara Spitzer; Birgitta Versluijs; Alwin Huitema; Caroline Lindemans; Stefan Nierkens; Jaap Jan Boelens
Journal:  Blood       Date:  2021-02-11       Impact factor: 22.113

Review 3.  The European Society for Blood and Marrow Transplantation (EBMT) consensus recommendations for donor selection in haploidentical hematopoietic cell transplantation.

Authors:  Stefan O Ciurea; Monzr M Al Malki; Piyanuch Kongtim; Ephraim J Fuchs; Leo Luznik; Xiao-Jun Huang; Fabio Ciceri; Franco Locatelli; Franco Aversa; Luca Castagna; Andrea Bacigalupo; Massimo Martelli; Didier Blaise; Patrick Ben Soussan; Yolande Arnault; Rupert Handgretinger; Denis-Claude Roy; Paul V O'Donnell; Asad Bashey; Scott Solomon; Rizwan Romee; Jorge Gayoso; Hillard M Lazarus; Karen Ballen; Bipin N Savani; Mohamad Mohty; Arnon Nagler
Journal:  Bone Marrow Transplant       Date:  2019-03-04       Impact factor: 5.483

4.  Haploidentical Stem Cell Transplantation in Children With Hematological Malignancies Using αβ+ T-Cell Receptor and CD19+ Cell Depleted Grafts: High CD56dim/CD56bright NK Cell Ratio Early Following Transplantation Is Associated With Lower Relapse Incidence and Better Outcome.

Authors:  Miguel A Diaz; Josune Zubicaray; Blanca Molina; Lorea Abad; Ana Castillo; Elena Sebastian; Eva Galvez; Julia Ruiz; Jose Luis Vicario; Manuel Ramirez; Julian Sevilla; Marta González-Vicent
Journal:  Front Immunol       Date:  2019-10-30       Impact factor: 7.561

Review 5.  Immune Reconstitution in the Aging Host: Opportunities for Mechanism-Based Therapy in Allogeneic Hematopoietic Cell Transplantation.

Authors:  Richard J Lin; Harold K Elias; Marcel R M van den Brink
Journal:  Front Immunol       Date:  2021-04-19       Impact factor: 7.561

Review 6.  HLA-Haploidentical Family Donors: The New Promise for Childhood Acute Lymphoblastic Leukaemia?

Authors:  Syaza Ab Rahman; Toni Matic; Maya Yordanova; Hany Ariffin
Journal:  Front Pediatr       Date:  2022-01-21       Impact factor: 3.418

7.  T-Cell Depleted Haploidentical Transplantation in Children With Hematological Malignancies: A Comparison Between CD3+/CD19+ and TCRαβ+/CD19+ Depletion Platforms.

Authors:  Marta Gonzalez-Vicent; Blanca Molina; Ivan Lopez; Josune Zubicaray; Julia Ruiz; Jose Luis Vicario; Elena Sebastián; June Iriondo; Ana Castillo; Lorea Abad; Manuel Ramirez; Julian Sevilla; Miguel A Diaz
Journal:  Front Oncol       Date:  2022-06-20       Impact factor: 5.738

Review 8.  T cell regeneration after immunological injury.

Authors:  Enrico Velardi; Jennifer J Tsai; Marcel R M van den Brink
Journal:  Nat Rev Immunol       Date:  2020-10-23       Impact factor: 53.106

9.  Long-term mid-onset dietary restriction rejuvenates hematopoietic stem cells and improves regeneration capacity of total bone marrow from aged mice.

Authors:  Si Tao; Yiting Wang; Jianying Wu; Ting Zeng; Hui Cui; Zhendong Tao; Lang Lei; Li Yu; Anwen Liu; Hua Wang; Liu Zhang; Duozhuang Tang
Journal:  Aging Cell       Date:  2020-09-15       Impact factor: 9.304
  9 in total

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