Literature DB >> 28292560

Application of Mosher's method for absolute configuration assignment to bioactive plants and fungi metabolites.

Alessio Cimmino1, Marco Masi1, Marco Evidente1, Stefano Superchi2, Antonio Evidente3.   

Abstract

The review deals with the application of the NMR advanced Mosher's method for the assignment of the absolute configuration to plant and fungal metabolites belonging to different classes of natural compounds. The structural and stereochemical characterization of these naturally occurring metabolites, as well as their biological properties as possible drugs or agrochemicals is reviewed. The importance of the absolute and relative stereochemistry on their biological properties is also highlighted. Successes and failures of application of the advanced Mosher's method are reported.
Copyright © 2017 Elsevier B.V. All rights reserved.

Keywords:  Absolute configuration; Advanced Mosher’s method; Biological activity; Chiral natural products; Plant and fungi metabolites

Mesh：

Year:  2017        PMID： 28292560     DOI： 10.1016/j.jpba.2017.02.037

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN： 0731-7085            Impact factor:   3.935


  13 in total

1.  Structure elucidation and absolute configuration of metabolites from the soil-derived fungus Dictyosporium digitatum using spectroscopic and computational methods.

Authors:  Trong D Tran; Brice A P Wilson; Curtis J Henrich; Karen L Wendt; Jarrod King; Robert H Cichewicz; Alberto M Stchigel; Andrew N Miller; Barry R O'Keefe; Kirk R Gustafson
Journal:  Phytochemistry       Date:  2020-02-17       Impact factor: 4.072

Review 2.  Fungal Metabolite Antagonists of Plant Pests and Human Pathogens: Structure-Activity Relationship Studies.

Authors:  Marco Masi; Paola Nocera; Pierluigi Reveglia; Alessio Cimmino; Antonio Evidente
Journal:  Molecules       Date:  2018-04-05       Impact factor: 4.411

3.  Assignment Through Chiroptical Methods of The Absolute Configuration of Fungal Dihydropyranpyran-4-5-Diones Phytotoxins, Potential Herbicides for Buffelgrass (Cenchrus ciliaris) Biocontrol.

Authors:  Ernesto Santoro; Giuseppe Mazzeo; Giulia Marsico; Marco Masi; Giovanna Longhi; Stefano Superchi; Antonio Evidente; Sergio Abbate
Journal:  Molecules       Date:  2019-08-21       Impact factor: 4.411

4.  Characterization of stereoisomeric 5-(2-nitro-1-phenylethyl)furan-2(5H)-ones by computation of 1 H and 13 C NMR chemical shifts and electronic circular dichroism spectra.

Authors:  Dayane T Lopes; Thomas R Hoye; Elson S Alvarenga
Journal:  Magn Reson Chem       Date:  2020-07-15       Impact factor: 2.447

5.  Absolute Configuration Determination of Retroflexanone Using the Advanced Mosher Method and Application of HPLC-NMR.

Authors:  Caleb Singleton; Robert Brkljača; Sylvia Urban
Journal:  Mar Drugs       Date:  2018-06-12       Impact factor: 5.118

6.  Phytotoxic Activity of Metabolites Isolated from Rutstroemia sp.n., the Causal Agent of Bleach Blonde Syndrome on Cheatgrass (Bromus tectorum).

Authors:  Marco Masi; Susan Meyer; Marcin Górecki; Gennaro Pescitelli; Suzette Clement; Alessio Cimmino; Antonio Evidente
Journal:  Molecules       Date:  2018-07-16       Impact factor: 4.411

7.  Phytotoxic Metabolites Isolated from Neufusicoccum batangarum, the Causal Agent of the Scabby Canker of Cactus Pear (Opuntia ficus-indica L.).

Authors:  Marco Masi; Francesco Aloi; Paola Nocera; Santa Olga Cacciola; Giuseppe Surico; Antonio Evidente
Journal:  Toxins (Basel)       Date:  2020-02-18       Impact factor: 4.546

8.  Absolute Configuration Assignment to Chiral Natural Products by Biphenyl Chiroptical Probes: The Case of the Phytotoxins Colletochlorin A and Agropyrenol.

Authors:  Ernesto Santoro; Stefania Vergura; Patrizia Scafato; Sandra Belviso; Marco Masi; Antonio Evidente; Stefano Superchi
Journal:  J Nat Prod       Date:  2020-02-24       Impact factor: 4.050

9.  The Assignment of the Absolute Configuration of Non-Cyclic Sesquiterpenes by Vibrational and Electronic Circular Dichroism: The Example of Chiliadenus lopadusanus Metabolites.

Authors:  Giuseppe Mazzeo; Alessio Cimmino; Giovanna Longhi; Marco Masi; Antonio Evidente; Sergio Abbate
Journal:  Biomolecules       Date:  2021-12-18

10.  Computational Approaches and Use of Chiroptical Probes in the Absolute Configuration Assignment to Natural Products by ECD Spectroscopy: A 1,2,3-Trihydroxy-p-menthane as a Case Study.

Authors:  Giulia Marsico; Umberto Calice; Patrizia Scafato; Sandra Belviso; Antonio Evidente; Stefano Superchi
Journal:  Biomolecules       Date:  2022-03-09
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.