Ana M Palomar1, Aránzazu Portillo1, Sonia Santibáñez1, Lara García-Álvarez1, Agustín Muñoz-Sanz2, Francisco J Márquez3, Lourdes Romero1, José M Eiros4, José A Oteo5. 1. Centro de Rickettsiosis y Enfermedades Transmitidas por Artrópodos Vectores, Departamento de Enfermedades Infecciosas, Hospital San Pedro-CIBIR, Logroño, Spain. 2. Servicio de Patología Infecciosa, Hospital Universitario de Badajoz, Badajoz, Spain. 3. Departamento de Biología Animal, Biología Vegetal y Ecología, Universidad de Jaén, Facultad de Ciencias Experimentales, Jaén, Spain. 4. Facultad de Medicina, Universidad de Valladolid, Microbiología, Valladolid, Spain. 5. Centro de Rickettsiosis y Enfermedades Transmitidas por Artrópodos Vectores, Departamento de Enfermedades Infecciosas, Hospital San Pedro-CIBIR, Logroño, Spain. Electronic address: jaoteo@riojasalud.es.
Abstract
INTRODUCTION: Crimean-Congo hemorrhagic fever (CCHF) is a viral disease, mainly transmitted through tick bite, of great importance in Public Health. In Spain, Crimean-Congo hemorrhagic fever virus (CCHFV) was detected for the first time in 2010 in Hyalomma lusitanicum ticks collected from deer in Cáceres. The aim of this study was to investigate the presence of CCHFV in ticks from Cáceres, and from other Spanish areas, and to evaluate the presence of antibodies against the virus in individuals exposed to tick bites. METHODS: A total of 2053 ticks (1333 Hyalomma marginatum, 680 H. lusitanicum and 40 Rhipicephalus bursa) were analyzed using molecular biology techniques (PCR) for CCHFV detection. The determination of specific IgG antibodies against CCHFV in 228 serum samples from humans with regular contact with ticks (at risk of acquiring the infection) was performed by indirect immunofluorescence assay. RESULTS: The CCHFV was not amplified in ticks, nor were antibodies against the virus found in the serum samples analyzed. CONCLUSION: The absence of the CCHFV in the ticks studied and the lack of antibodies against the virus in individuals exposed to tick bites would seem to suggest a low risk of acquisition of human infection by CCHFV in Spain.
INTRODUCTION:Crimean-Congo hemorrhagic fever (CCHF) is a viral disease, mainly transmitted through tick bite, of great importance in Public Health. In Spain, Crimean-Congo hemorrhagic fever virus (CCHFV) was detected for the first time in 2010 in Hyalomma lusitanicum ticks collected from deer in Cáceres. The aim of this study was to investigate the presence of CCHFV in ticks from Cáceres, and from other Spanish areas, and to evaluate the presence of antibodies against the virus in individuals exposed to tick bites. METHODS: A total of 2053 ticks (1333 Hyalomma marginatum, 680 H. lusitanicum and 40 Rhipicephalus bursa) were analyzed using molecular biology techniques (PCR) for CCHFV detection. The determination of specific IgG antibodies against CCHFV in 228 serum samples from humans with regular contact with ticks (at risk of acquiring the infection) was performed by indirect immunofluorescence assay. RESULTS: The CCHFV was not amplified in ticks, nor were antibodies against the virus found in the serum samples analyzed. CONCLUSION: The absence of the CCHFV in the ticks studied and the lack of antibodies against the virus in individuals exposed to tick bites would seem to suggest a low risk of acquisition of humaninfection by CCHFV in Spain.
Authors: Ana Negredo; Miguel Ángel Habela; Eva Ramírez de Arellano; Francisco Diez; Fátima Lasala; Pablo López; Ana Sarriá; Nuria Labiod; Rafael Calero-Bernal; Miguel Arenas; Antonio Tenorio; Agustín Estrada-Peña; Maria Paz Sánchez-Seco Journal: Emerg Infect Dis Date: 2019-06 Impact factor: 6.883
Authors: Lía Monsalve Arteaga; Juan Luis Muñoz Bellido; María Carmen Vieira Lista; María Belén Vicente Santiago; Pedro Fernández Soto; Isabel Bas; Nuria Leralta; Fernando de Ory Manchón; Ana Isabel Negredo; María Paz Sánchez Seco; Montserrat Alonso Sardón; Sonia Pérez González; Ana Jiménez Del Bianco; Lydia Blanco Peris; Rufino Alamo-Sanz; Roger Hewson; Moncef Belhassen-García; Antonio Muro Journal: Euro Surveill Date: 2020-03