Guo Zhong Chen1, Song Luo1, Chang Sheng Zhou1, Long Jiang Zhang2, Guang Ming Lu3. 1. Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, 210002, China. 2. Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, 210002, China. kevinzhlj@163.com. 3. Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, 210002, China. cjr.luguangming@vip.163.com.
Abstract
OBJECTIVE: To evaluate the diagnostic accuracy of digital subtraction CT angiography (DS-CTA) in detecting posterior inferior cerebellar artery (PICA) aneurysms with digital subtraction angiography (DSA) as reference standard. METHODS: A total of 115 patients, including 56 patients diagnosed with PICA aneurysms by CTA or DSA and 59 non-PICA-aneurysm patients were included in this retrospective study. All patients underwent DS-CTA and DSA. The site of PICA aneurysms and the pattern of haemorrhage were analysed. Sensitivity and specificity of DS-CTA without and with combining haemorrhage pattern in diagnosing PICA aneurysms were evaluated on a per patient and per aneurysm basis with DSA. RESULTS: Of 115 patients, 56 patients (48.7%) had 61 PICA aneurysms (size range, 1.1-13.5 mm; mean size, 4.9 ± 2.8 mm) on DSA. The sensitivity and specificity in depicting PICA aneurysms were 89.3% and 96.6% on a per patient basis and 90.2% and 93.4% on a per aneurysm basis, while the corresponding values were 94.6% and 96.6% on a per patient basis and 95.1% and 93.4% on a per aneurysm basis when combining with haemorrhage site. CONCLUSION: DS-CTA has a high sensitivity and specificity in detecting PICA aneurysms compared with DSA. It may be helpful for clinical diagnosis of PICA aneurysms to combine with haemorrhage sites. KEY POINTS: • CT angiography has a good diagnostic performance in detecting PICA aneurysms. • The haemorrhage location is helpful to detect PICA aneurysms. • Digital subtraction CTA is a preferable diagnostic means for PICA aneurysms.
OBJECTIVE: To evaluate the diagnostic accuracy of digital subtraction CT angiography (DS-CTA) in detecting posterior inferior cerebellar artery (PICA) aneurysms with digital subtraction angiography (DSA) as reference standard. METHODS: A total of 115 patients, including 56 patients diagnosed with PICAaneurysms by CTA or DSA and 59 non-PICA-aneurysmpatients were included in this retrospective study. All patients underwent DS-CTA and DSA. The site of PICAaneurysms and the pattern of haemorrhage were analysed. Sensitivity and specificity of DS-CTA without and with combining haemorrhage pattern in diagnosing PICAaneurysms were evaluated on a per patient and per aneurysm basis with DSA. RESULTS: Of 115 patients, 56 patients (48.7%) had 61 PICAaneurysms (size range, 1.1-13.5 mm; mean size, 4.9 ± 2.8 mm) on DSA. The sensitivity and specificity in depicting PICAaneurysms were 89.3% and 96.6% on a per patient basis and 90.2% and 93.4% on a per aneurysm basis, while the corresponding values were 94.6% and 96.6% on a per patient basis and 95.1% and 93.4% on a per aneurysm basis when combining with haemorrhage site. CONCLUSION:DS-CTA has a high sensitivity and specificity in detecting PICAaneurysms compared with DSA. It may be helpful for clinical diagnosis of PICAaneurysms to combine with haemorrhage sites. KEY POINTS: • CT angiography has a good diagnostic performance in detecting PICAaneurysms. • The haemorrhage location is helpful to detect PICAaneurysms. • Digital subtraction CTA is a preferable diagnostic means for PICAaneurysms.
Authors: Henriëtte E Westerlaan; J M C van Dijk; M J van Dijk; Marijke C Jansen-van der Weide; Jan Cees de Groot; Rob J M Groen; Jan Jakob A Mooij; Matthijs Oudkerk Journal: Radiology Date: 2010-10-08 Impact factor: 11.105