Literature DB >> 2828980

Autoradiographic localization of opioid receptor types in the rat small intestine.

M R Dashwood1, R M Sykes, C S Thompson.   

Abstract

The selective mu and delta ligands [3H]DAGO and [3H]DPDPE have been used to investigate the distribution of specific opioid subtypes in the rat small intestine by in vitro autoradiography. There was a greater density of [3H]DPDPE binding at regions of the villi and crypts than [3H]DAGO binding. These results suggest that the opioid receptors located in these regions are predominantly of the delta subtype.

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Year:  1986        PMID: 2828980

Source DB:  PubMed          Journal:  NIDA Res Monogr        ISSN: 1046-9516


  1 in total

1.  Differential cardiovascular and respiratory responses to central administration of selective opioid agonists in conscious rabbits: correlation with receptor distribution.

Authors:  C N May; M R Dashwood; C J Whitehead; C J Mathias
Journal:  Br J Pharmacol       Date:  1989-11       Impact factor: 8.739

  1 in total

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