Literature DB >> 28289789

[Medical care of patients with spasticity following stroke : Evaluation of the treatment situation in Germany with focus on the use of botulinum toxin].

L Kerkemeyer1, G Lux2, A Walendzik2, J Wasem2, A Neumann2.   

Abstract

BACKGROUND: Upper limb spasticity is a common complication following stroke. Cohort studies found 19% of post-stroke patients had upper limb spasticity at 3 months and 38% of patients at 12 months. For focal spasticity, intramuscular injections of botulinum toxin are indicated. In Germany, it is assumed that patients with the described indication are undersupplied with botulinum toxin.
OBJECTIVE: The aim of the present study is to evaluate the medical care of patients with upper limb spasticity post-stroke with the focus on the use of botulinum toxin as one treatment option.
METHODS: A standardized questionnaire was developed and a postal survey of a representative national random sample of 800 neurologists to capture the actual medical care situation.
RESULTS: The response rate amounted to 37% (n = 292). 59% of the neurologists surveyed had never used botulinum toxin. In total, 87% of neurologists noticed barriers regarding the use of botulinum toxin, where the amount of the doctor's remuneration in 40% and the lack of reimbursement of costs in off-label use in 60% were the most commonly used answers. The achievement of an advanced training in using botulinum toxin was also stated as a general obstacle for resident neurologists. DISCUSSION: Due to a response rate of 37% for the postal survey a selection bias cannot be excluded. Although botulinum toxin is recommended in the national treatment guidelines, many neurologists do not use botulinum toxin. The reasons can be seen from the barriers described.

Entities:  

Keywords:  Botulinum toxins Type A; Evaluation; Standardized survey

Mesh:

Substances:

Year:  2017        PMID: 28289789     DOI: 10.1007/s00115-017-0312-4

Source DB:  PubMed          Journal:  Nervenarzt        ISSN: 0028-2804            Impact factor:   1.214


  16 in total

1.  [Projection of the number of multiple sclerosis patients in Germany].

Authors:  T Hein; W Hopfenmüller
Journal:  Nervenarzt       Date:  2000-04       Impact factor: 1.214

2.  [Botulinum toxin in the treatment of adult spasticity. An interdisciplinary German 10-point consensus 2010].

Authors:  J Wissel; M auf dem Brinke; M Hecht; C Herrmann; M Huber; S Mehnert; I Reuter; A Schramm; A Stenner; C van der Ven; M Winterholler; A Kupsch
Journal:  Nervenarzt       Date:  2011-04       Impact factor: 1.214

3.  Safety and efficacy of abobotulinumtoxinA for hemiparesis in adults with upper limb spasticity after stroke or traumatic brain injury: a double-blind randomised controlled trial.

Authors:  Jean-Michel Gracies; Allison Brashear; Robert Jech; Peter McAllister; Marta Banach; Peter Valkovic; Heather Walker; Christina Marciniak; Thierry Deltombe; Alexander Skoromets; Svetlana Khatkova; Steven Edgley; Fatma Gul; France Catus; Beatrice Bois De Fer; Claire Vilain; Philippe Picaut
Journal:  Lancet Neurol       Date:  2015-08-26       Impact factor: 44.182

4.  Practice guideline update summary: Botulinum neurotoxin for the treatment of blepharospasm, cervical dystonia, adult spasticity, and headache: Report of the Guideline Development Subcommittee of the American Academy of Neurology.

Authors:  David M Simpson; Mark Hallett; Eric J Ashman; Cynthia L Comella; Mark W Green; Gary S Gronseth; Melissa J Armstrong; David Gloss; Sonja Potrebic; Joseph Jankovic; Barbara P Karp; Markus Naumann; Yuen T So; Stuart A Yablon
Journal:  Neurology       Date:  2016-04-18       Impact factor: 9.910

5.  Efficacy and safety of treatment with incobotulinum toxin A (botulinum neurotoxin type A free from complexing proteins; NT 201) in post-stroke upper limb spasticity.

Authors:  Petr Kaňovský; Jaroslaw Slawek; Zoltan Denes; Thomas Platz; Georg Comes; Susanne Grafe; Irena Pulte
Journal:  J Rehabil Med       Date:  2011-05       Impact factor: 2.912

6.  Intramuscular injection of botulinum toxin for the treatment of wrist and finger spasticity after a stroke.

Authors:  Allison Brashear; Mark F Gordon; Elie Elovic; V Daniel Kassicieh; Christina Marciniak; Mai Do; Chia-Ho Lee; Stephen Jenkins; Catherine Turkel
Journal:  N Engl J Med       Date:  2002-08-08       Impact factor: 91.245

7.  Spasticity after stroke: its occurrence and association with motor impairments and activity limitations.

Authors:  Disa K Sommerfeld; Elsy U-B Eek; Anna-Karin Svensson; Lotta Widén Holmqvist; Magnus H von Arbin
Journal:  Stroke       Date:  2003-12-18       Impact factor: 7.914

8.  Efficacy and safety of botulinum neurotoxin NT 201 in poststroke upper limb spasticity.

Authors:  Petr Kanovský; Jaroslaw Slawek; Zoltan Denes; Thomas Platz; Irena Sassin; Georg Comes; Susanne Grafe
Journal:  Clin Neuropharmacol       Date:  2009 Sep-Oct       Impact factor: 1.592

9.  Prevalence of spasticity post stroke.

Authors:  C L Watkins; M J Leathley; J M Gregson; A P Moore; T L Smith; A K Sharma
Journal:  Clin Rehabil       Date:  2002-08       Impact factor: 3.477

10.  Randomized, placebo-controlled trial of incobotulinumtoxina for upper-limb post-stroke spasticity.

Authors:  Elie Paul Elovic; Michael C Munin; Petr Kaňovský; Angelika Hanschmann; Reinhard Hiersemenzel; Christina Marciniak
Journal:  Muscle Nerve       Date:  2015-12-15       Impact factor: 3.217

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.